To determine the relation of mean platelet volume with diabetes mellitus
Background: Diabetes mellitus (DM) is a complex metabolic disorder portrayed by chronic hyperglycemia bringing about intricacies influencing the peripheral nerves, kidneys, eyes, and macrovascular structures. Mean platelet volume (MPV) is also considered to impact the advancement of microvascular co...
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| Format: | Article |
| Language: | English |
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Manipal College of Medical Sciences, Pokhara
2022-09-01
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| Series: | Asian Journal of Medical Sciences |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/44690 |
| _version_ | 1828109542770081792 |
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| author | Milind Jivanlal Manvar Rajesh Sukumar Roy Viralkumar Mohanbhai Jadav Amalkumar Bankimchandra Bhattacharya |
| author_facet | Milind Jivanlal Manvar Rajesh Sukumar Roy Viralkumar Mohanbhai Jadav Amalkumar Bankimchandra Bhattacharya |
| author_sort | Milind Jivanlal Manvar |
| collection | DOAJ |
| description | Background: Diabetes mellitus (DM) is a complex metabolic disorder portrayed by chronic hyperglycemia bringing about intricacies influencing the peripheral nerves, kidneys, eyes, and macrovascular structures. Mean platelet volume (MPV) is also considered to impact the advancement of microvascular complications of diabetes mellitus which has been looked for in this study.
Aims and Objectives: The aims of this study were as follows: (1) To study association of MPV with Nephropathy and Retinopathy in Diabetes. (2) To Study correlation of MPV with hemoglobin A1c (HbA1C), fasting blood sugar, post-prandial blood sugar, and body mass index (BMI).
Materials and Methods: This was an observational study conducted over 18 months period on patients (both males and females) seeking medical attention for newly diagnosed or previously diagnosed DM. Selective sampling technique was used and 200 diabetic patients were enrolled in the study during the study period.
Results: (1) The incidence of retinopathy and increased Hba1c was significantly higher in poorly controlled diabetics as compared to controlled diabetics. (2) In good glycemic control group, mean MPV was 8.58 fL and, in poor glycemic control group, mean MPV was 10.21 fL.
Conclusion: There was a positive correlation between MPV and HbA1C, microalbuminuria, BMI, fasting, and post-prandial blood sugar levels. There was no significant association between MPV and retinopathy. |
| first_indexed | 2024-04-11T11:05:09Z |
| format | Article |
| id | doaj.art-6838dc3279d947eeb0743025d1f1ca97 |
| institution | Directory Open Access Journal |
| issn | 2467-9100 2091-0576 |
| language | English |
| last_indexed | 2024-04-11T11:05:09Z |
| publishDate | 2022-09-01 |
| publisher | Manipal College of Medical Sciences, Pokhara |
| record_format | Article |
| series | Asian Journal of Medical Sciences |
| spelling | doaj.art-6838dc3279d947eeb0743025d1f1ca972022-12-22T04:28:24ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762022-09-01139130135https://doi.org/10.3126/ajms.v13i9.44690To determine the relation of mean platelet volume with diabetes mellitusMilind Jivanlal Manvar 0https://orcid.org/0000-0002-6117-1802Rajesh Sukumar Roy 1https://orcid.org/0000-0002-1470-1727Viralkumar Mohanbhai Jadav 2https://orcid.org/0000-0001-9803-3705Amalkumar Bankimchandra Bhattacharya 3https://orcid.org/0000-0002-7844-0132Assistant Professor, Department of Medicine, Parul Institute of Medical Sciences and Research, Parul University, Vadodara, Gujarat, India Associate Professor, Department of Medicine, Parul Institute of Medical Sciences and Research, Parul University, Vadodara, Gujarat, India Assistant Professor, Department of Medicine, Parul Institute of Medical Sciences and Research, Parul University, Vadodara, Gujarat, India Professor and Head, Department of Medicine, Parul Institute of Medical Sciences and Research, Parul University, Vadodara, Gujarat, India Background: Diabetes mellitus (DM) is a complex metabolic disorder portrayed by chronic hyperglycemia bringing about intricacies influencing the peripheral nerves, kidneys, eyes, and macrovascular structures. Mean platelet volume (MPV) is also considered to impact the advancement of microvascular complications of diabetes mellitus which has been looked for in this study. Aims and Objectives: The aims of this study were as follows: (1) To study association of MPV with Nephropathy and Retinopathy in Diabetes. (2) To Study correlation of MPV with hemoglobin A1c (HbA1C), fasting blood sugar, post-prandial blood sugar, and body mass index (BMI). Materials and Methods: This was an observational study conducted over 18 months period on patients (both males and females) seeking medical attention for newly diagnosed or previously diagnosed DM. Selective sampling technique was used and 200 diabetic patients were enrolled in the study during the study period. Results: (1) The incidence of retinopathy and increased Hba1c was significantly higher in poorly controlled diabetics as compared to controlled diabetics. (2) In good glycemic control group, mean MPV was 8.58 fL and, in poor glycemic control group, mean MPV was 10.21 fL. Conclusion: There was a positive correlation between MPV and HbA1C, microalbuminuria, BMI, fasting, and post-prandial blood sugar levels. There was no significant association between MPV and retinopathy.https://www.nepjol.info/index.php/AJMS/article/view/44690diabetes mellitus; hemoglobin a1c; mean platelet volume |
| spellingShingle | Milind Jivanlal Manvar Rajesh Sukumar Roy Viralkumar Mohanbhai Jadav Amalkumar Bankimchandra Bhattacharya To determine the relation of mean platelet volume with diabetes mellitus Asian Journal of Medical Sciences diabetes mellitus; hemoglobin a1c; mean platelet volume |
| title | To determine the relation of mean platelet volume with diabetes mellitus |
| title_full | To determine the relation of mean platelet volume with diabetes mellitus |
| title_fullStr | To determine the relation of mean platelet volume with diabetes mellitus |
| title_full_unstemmed | To determine the relation of mean platelet volume with diabetes mellitus |
| title_short | To determine the relation of mean platelet volume with diabetes mellitus |
| title_sort | to determine the relation of mean platelet volume with diabetes mellitus |
| topic | diabetes mellitus; hemoglobin a1c; mean platelet volume |
| url | https://www.nepjol.info/index.php/AJMS/article/view/44690 |
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