An approach for automatic lesion detection in mammograms

Early stage breast cancer detection can reduce death rates in long term. Mammography is the current standard screening tool available for breast cancer detection, but it is found to have high false-positive and false-negative rates. This may be due to poor quality of mammograms, subtle nature of mal...

Full description

Bibliographic Details
Main Authors: K.U. Sheba, S. Gladston Raj
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Cogent Engineering
Subjects:
Online Access:http://dx.doi.org/10.1080/23311916.2018.1444320
_version_ 1797721640338980864
author K.U. Sheba
S. Gladston Raj
author_facet K.U. Sheba
S. Gladston Raj
author_sort K.U. Sheba
collection DOAJ
description Early stage breast cancer detection can reduce death rates in long term. Mammography is the current standard screening tool available for breast cancer detection, but it is found to have high false-positive and false-negative rates. This may be due to poor quality of mammograms, subtle nature of malignancies and limitations in human/brain visual system. The aim of this research work is to develop an efficient classification tool with improved breast screening accuracy to distinguish between healthy, benign and malignant breast parenchyma in digital mammograms. This paper presents a computer aided diagnosis system for automated detection and diagnosis of breast cancer in digital mammograms. The proposed system can be used as a reference reader for double reading the mammograms and thus assisting the radiologists in clinical diagnosis by indicating suspicious abnormalities. This can improve the diagnostic performance of the radiologists. In the proposed methodology, the regions of interest (ROI) are automatically detected and segmented from mammograms using global thresholding, Otsu’s method and morphological operations. Shape, texture and grey-level features are extracted from the ROIs. Optimal features are selected using Classifier and Regression Tree (CART). Classification is performed with Feed forward artificial neural networks using back propagation. Performance is evaluated using Receiver Operating Characteristic (ROC) analysis and confusion matrix. Experimental results show that the proposed method achieved an accuracy of 96% with 83% sensitivity and 98% specificity. The proposed methodology has been compared with several other classification models and is found to have a good performance in terms of accuracy, sensitivity and specificity.
first_indexed 2024-03-12T09:37:07Z
format Article
id doaj.art-683906b4574e4a7cb82fe28c87735aa0
institution Directory Open Access Journal
issn 2331-1916
language English
last_indexed 2024-03-12T09:37:07Z
publishDate 2018-01-01
publisher Taylor & Francis Group
record_format Article
series Cogent Engineering
spelling doaj.art-683906b4574e4a7cb82fe28c87735aa02023-09-02T13:33:54ZengTaylor & Francis GroupCogent Engineering2331-19162018-01-015110.1080/23311916.2018.14443201444320An approach for automatic lesion detection in mammogramsK.U. Sheba0S. Gladston Raj1BPC CollegeGovernment CollegeEarly stage breast cancer detection can reduce death rates in long term. Mammography is the current standard screening tool available for breast cancer detection, but it is found to have high false-positive and false-negative rates. This may be due to poor quality of mammograms, subtle nature of malignancies and limitations in human/brain visual system. The aim of this research work is to develop an efficient classification tool with improved breast screening accuracy to distinguish between healthy, benign and malignant breast parenchyma in digital mammograms. This paper presents a computer aided diagnosis system for automated detection and diagnosis of breast cancer in digital mammograms. The proposed system can be used as a reference reader for double reading the mammograms and thus assisting the radiologists in clinical diagnosis by indicating suspicious abnormalities. This can improve the diagnostic performance of the radiologists. In the proposed methodology, the regions of interest (ROI) are automatically detected and segmented from mammograms using global thresholding, Otsu’s method and morphological operations. Shape, texture and grey-level features are extracted from the ROIs. Optimal features are selected using Classifier and Regression Tree (CART). Classification is performed with Feed forward artificial neural networks using back propagation. Performance is evaluated using Receiver Operating Characteristic (ROC) analysis and confusion matrix. Experimental results show that the proposed method achieved an accuracy of 96% with 83% sensitivity and 98% specificity. The proposed methodology has been compared with several other classification models and is found to have a good performance in terms of accuracy, sensitivity and specificity.http://dx.doi.org/10.1080/23311916.2018.1444320grey-level co-occurrence matrixgrey level run length matrixotsu’s methodmorphological openfeed forward artificial neural networksglobal thresholding
spellingShingle K.U. Sheba
S. Gladston Raj
An approach for automatic lesion detection in mammograms
Cogent Engineering
grey-level co-occurrence matrix
grey level run length matrix
otsu’s method
morphological open
feed forward artificial neural networks
global thresholding
title An approach for automatic lesion detection in mammograms
title_full An approach for automatic lesion detection in mammograms
title_fullStr An approach for automatic lesion detection in mammograms
title_full_unstemmed An approach for automatic lesion detection in mammograms
title_short An approach for automatic lesion detection in mammograms
title_sort approach for automatic lesion detection in mammograms
topic grey-level co-occurrence matrix
grey level run length matrix
otsu’s method
morphological open
feed forward artificial neural networks
global thresholding
url http://dx.doi.org/10.1080/23311916.2018.1444320
work_keys_str_mv AT kusheba anapproachforautomaticlesiondetectioninmammograms
AT sgladstonraj anapproachforautomaticlesiondetectioninmammograms
AT kusheba approachforautomaticlesiondetectioninmammograms
AT sgladstonraj approachforautomaticlesiondetectioninmammograms