Aripriprazole induced severe oculogyric dystonia treated with electroconvulsive therapy(ECT)

Introduction Aripiprazole is the third generation Antipsychotic, and Dopamine serotonin system stabiliser.It is partial agonist at D2 and 5 HT1 A and antagonist at 5 HT2.Most commonly seen adverse effects are Akathesia, fatugue,insomnia and headache the major advanatage is less propensity for extra...

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Main Authors: K. Bhat Shah, T. S. Bhat, J. S. Pawar, N. Pande
Format: Article
Language:English
Published: Cambridge University Press 2023-03-01
Series:European Psychiatry
Online Access:https://www.cambridge.org/core/product/identifier/S0924933823021429/type/journal_article
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author K. Bhat Shah
T. S. Bhat
J. S. Pawar
N. Pande
author_facet K. Bhat Shah
T. S. Bhat
J. S. Pawar
N. Pande
author_sort K. Bhat Shah
collection DOAJ
description Introduction Aripiprazole is the third generation Antipsychotic, and Dopamine serotonin system stabiliser.It is partial agonist at D2 and 5 HT1 A and antagonist at 5 HT2.Most commonly seen adverse effects are Akathesia, fatugue,insomnia and headache the major advanatage is less propensity for extrapyramidal side effects and lmetabolic side eefects. Objectives To report a case of Schizophrenia treated with Aripiprazole 15mg/day developiing occular gyric crisis which was tratment resistant. Methods We administered Electroconvulsvive therapy, bidirectional brief pulse constant current 8 ECTS, under General anesthesia with medical fitness . Results Patient Showed complete resolution of Dystonia after second ECTs and Showed improvment in Pyschosis Parameterd. Assessment using Naranjo Protocol made. Conclusions Electroconvulsive therapy therapy is viable alternative to manage Dystonia when medical treatment fails Disclosure of Interest None Declared
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spelling doaj.art-683d2c17a1774a8bb178ab38e06dac092023-11-17T05:09:14ZengCambridge University PressEuropean Psychiatry0924-93381778-35852023-03-0166S1009S100910.1192/j.eurpsy.2023.2142Aripriprazole induced severe oculogyric dystonia treated with electroconvulsive therapy(ECT)K. Bhat Shah0T. S. Bhat1J. S. Pawar2N. Pande3Ophthalmology, JMF’S ACPM Medical College DhulePsychiatry, JMF’S ACPM Medical CollegePsychiatry, Shri Bhausaheb Hire Medical College, DhulePsychiatry, Orange City Hospital, Nagpur, India Introduction Aripiprazole is the third generation Antipsychotic, and Dopamine serotonin system stabiliser.It is partial agonist at D2 and 5 HT1 A and antagonist at 5 HT2.Most commonly seen adverse effects are Akathesia, fatugue,insomnia and headache the major advanatage is less propensity for extrapyramidal side effects and lmetabolic side eefects. Objectives To report a case of Schizophrenia treated with Aripiprazole 15mg/day developiing occular gyric crisis which was tratment resistant. Methods We administered Electroconvulsvive therapy, bidirectional brief pulse constant current 8 ECTS, under General anesthesia with medical fitness . Results Patient Showed complete resolution of Dystonia after second ECTs and Showed improvment in Pyschosis Parameterd. Assessment using Naranjo Protocol made. Conclusions Electroconvulsive therapy therapy is viable alternative to manage Dystonia when medical treatment fails Disclosure of Interest None Declaredhttps://www.cambridge.org/core/product/identifier/S0924933823021429/type/journal_article
spellingShingle K. Bhat Shah
T. S. Bhat
J. S. Pawar
N. Pande
Aripriprazole induced severe oculogyric dystonia treated with electroconvulsive therapy(ECT)
European Psychiatry
title Aripriprazole induced severe oculogyric dystonia treated with electroconvulsive therapy(ECT)
title_full Aripriprazole induced severe oculogyric dystonia treated with electroconvulsive therapy(ECT)
title_fullStr Aripriprazole induced severe oculogyric dystonia treated with electroconvulsive therapy(ECT)
title_full_unstemmed Aripriprazole induced severe oculogyric dystonia treated with electroconvulsive therapy(ECT)
title_short Aripriprazole induced severe oculogyric dystonia treated with electroconvulsive therapy(ECT)
title_sort aripriprazole induced severe oculogyric dystonia treated with electroconvulsive therapy ect
url https://www.cambridge.org/core/product/identifier/S0924933823021429/type/journal_article
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