The role of magnetic resonance imaging and magnetic resonance diffusion weighted image in preoperative staging of rectal cancer in comparison to postoperative histopathology
Background: With outstanding soft tissue contrast, functional imaging capabilities, and multiplanar capacity, high-resolution phased-array magnetic resonance imaging MRI is considered as a basic imaging modality for preoperative local staging of rectal cancer. And so MRI fills a void in clinical pra...
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| Format: | Article |
| Language: | English |
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South Valley University, Faculty of Medicine
2021-08-01
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| Series: | SVU - International Journal of Medical Sciences |
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| Online Access: | https://svuijm.journals.ekb.eg/article_194044.html |
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| author | Hamdey M. Hussien Ahmed Okasha Hind Nabil Abdelhay A. Abdelhay Mahmoud Abdelaziz Mohalil Orabi* |
| author_facet | Hamdey M. Hussien Ahmed Okasha Hind Nabil Abdelhay A. Abdelhay Mahmoud Abdelaziz Mohalil Orabi* |
| author_sort | Hamdey M. Hussien |
| collection | DOAJ |
| description | Background: With outstanding soft tissue contrast, functional imaging capabilities, and multiplanar capacity, high-resolution phased-array magnetic resonance imaging MRI is considered as a basic imaging modality for preoperative local staging of rectal cancer. And so MRI fills a void in clinical practice by allowing for precise local staging of rectal cancer prior to treatment decisions. The diffusion-weighted image used as enhancing utility for MRI in patients with rectal cancer.
Objectives: The aim of work was to assess the role of MRI imaging including the (diffusion weighted imaging DWI and Apparent diffusion coefficient ADC map) in preoperative rectal cancer staging, in comparison to post-operative histopathology.
Patients and methods: A total of 50 patients were included in the study, presented to South Valley University hospital and underwent MRI examination in MRI unit at South Valley University hospital.
Results: Regarding the circumferential resection margin (CRM) infiltration, MRI diagnosed CRM involvement in 15 cases while rest 35 cases showing free CRM. From these positive cases only 13 were truly positive with histopathology, other two cases proved to be positive with histopathology not diagnosed by MRI. MRI showed MRF infiltration in only 18 cases. Histopathological assessment showed that MRF infiltration in only 15 cases and the rest 35 cases showing free MRF (agreement 83.3%).
Conclusion: The results of this study demonstrate that preoperative MRI has a great value in achieving the best treatment strategy through accurate staging of rectal cancer, prediction of negative CRMs and involvement of the perirectal and pelvic LNs. |
| first_indexed | 2024-04-13T02:32:54Z |
| format | Article |
| id | doaj.art-683e0ac6995e40d7a4b0fce91a95e5e6 |
| institution | Directory Open Access Journal |
| issn | 2735-427X 2636-3402 |
| language | English |
| last_indexed | 2024-04-13T02:32:54Z |
| publishDate | 2021-08-01 |
| publisher | South Valley University, Faculty of Medicine |
| record_format | Article |
| series | SVU - International Journal of Medical Sciences |
| spelling | doaj.art-683e0ac6995e40d7a4b0fce91a95e5e62022-12-22T03:06:30ZengSouth Valley University, Faculty of MedicineSVU - International Journal of Medical Sciences2735-427X2636-34022021-08-0142269276https://dx.doi.org/10.21608/svuijm.2021.90832.1208The role of magnetic resonance imaging and magnetic resonance diffusion weighted image in preoperative staging of rectal cancer in comparison to postoperative histopathologyHamdey M. Hussien0 Ahmed Okasha1 Hind Nabil2Abdelhay A. Abdelhay3 Mahmoud Abdelaziz Mohalil Orabi*4General Surgery Department, Faculty of Medicine, Luxor University, Luxor, EgyptDiagnostic Radiology Department, Faculty of Medicine, South Valley University, Qena, EgyptDiagnostic Radiology Department, Faculty of Medicine, South Valley University, Qena, EgyptDiagnostic Radiology Department, Faculty of Medicine, Cairo University, Cairo, EgyptDiagnostic Radiology Department, Faculty of Medicine, South Valley University, Qena, EgyptBackground: With outstanding soft tissue contrast, functional imaging capabilities, and multiplanar capacity, high-resolution phased-array magnetic resonance imaging MRI is considered as a basic imaging modality for preoperative local staging of rectal cancer. And so MRI fills a void in clinical practice by allowing for precise local staging of rectal cancer prior to treatment decisions. The diffusion-weighted image used as enhancing utility for MRI in patients with rectal cancer. Objectives: The aim of work was to assess the role of MRI imaging including the (diffusion weighted imaging DWI and Apparent diffusion coefficient ADC map) in preoperative rectal cancer staging, in comparison to post-operative histopathology. Patients and methods: A total of 50 patients were included in the study, presented to South Valley University hospital and underwent MRI examination in MRI unit at South Valley University hospital. Results: Regarding the circumferential resection margin (CRM) infiltration, MRI diagnosed CRM involvement in 15 cases while rest 35 cases showing free CRM. From these positive cases only 13 were truly positive with histopathology, other two cases proved to be positive with histopathology not diagnosed by MRI. MRI showed MRF infiltration in only 18 cases. Histopathological assessment showed that MRF infiltration in only 15 cases and the rest 35 cases showing free MRF (agreement 83.3%). Conclusion: The results of this study demonstrate that preoperative MRI has a great value in achieving the best treatment strategy through accurate staging of rectal cancer, prediction of negative CRMs and involvement of the perirectal and pelvic LNs.https://svuijm.journals.ekb.eg/article_194044.htmldiffusion-weighted image; magnetic resonance imaging; rectal cancer; histopathology |
| spellingShingle | Hamdey M. Hussien Ahmed Okasha Hind Nabil Abdelhay A. Abdelhay Mahmoud Abdelaziz Mohalil Orabi* The role of magnetic resonance imaging and magnetic resonance diffusion weighted image in preoperative staging of rectal cancer in comparison to postoperative histopathology SVU - International Journal of Medical Sciences diffusion-weighted image; magnetic resonance imaging; rectal cancer; histopathology |
| title | The role of magnetic resonance imaging and magnetic resonance diffusion weighted image in preoperative staging of rectal cancer in comparison to postoperative histopathology |
| title_full | The role of magnetic resonance imaging and magnetic resonance diffusion weighted image in preoperative staging of rectal cancer in comparison to postoperative histopathology |
| title_fullStr | The role of magnetic resonance imaging and magnetic resonance diffusion weighted image in preoperative staging of rectal cancer in comparison to postoperative histopathology |
| title_full_unstemmed | The role of magnetic resonance imaging and magnetic resonance diffusion weighted image in preoperative staging of rectal cancer in comparison to postoperative histopathology |
| title_short | The role of magnetic resonance imaging and magnetic resonance diffusion weighted image in preoperative staging of rectal cancer in comparison to postoperative histopathology |
| title_sort | role of magnetic resonance imaging and magnetic resonance diffusion weighted image in preoperative staging of rectal cancer in comparison to postoperative histopathology |
| topic | diffusion-weighted image; magnetic resonance imaging; rectal cancer; histopathology |
| url | https://svuijm.journals.ekb.eg/article_194044.html |
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