Sexual dimorphism in obesity is governed by RELMα regulation of adipose macrophages and eosinophils

Sexual dimorphism in obesity is governed by RELMα regulation of adipose macrophages and eosinophils

Obesity incidence is increasing worldwide with the urgent need to identify new therapeutics. Sex differences in immune cell activation drive obesity-mediated pathologies where males are more susceptible to obesity comorbidities and exacerbated inflammation. Here, we demonstrate that the macrophage-s...

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Bibliographic Details
Main Authors: Jiang Li, Rebecca E Ruggiero-Ruff, Yuxin He, Xinru Qiu, Nancy Lainez, Pedro Villa, Adam Godzik, Djurdjica Coss, Meera G Nair
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-05-01
Series:eLife
Subjects:
macrophage
eosinophil
obesity
sexual dimorphism
adipose
RELMα
Online Access:https://elifesciences.org/articles/86001

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