CpGs Induce Differentiation of Atlantic Salmon Mononuclear Phagocytes Into Cells With Dendritic Morphology and a Proinflammatory Transcriptional Profile but an Exhausted Allostimulatory Activity

CpGs Induce Differentiation of Atlantic Salmon Mononuclear Phagocytes Into Cells With Dendritic Morphology and a Proinflammatory Transcriptional Profile but an Exhausted Allostimulatory Activity

Due to their ability to present foreign antigens and prime naïve T cells, macrophages, and dendritic cells (DCs) are referred to as professional antigen-presenting cells (APCs). Although activated macrophages may function as APCs, these cells are particularly effective at directly engaging pathogens...

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Bibliographic Details
Main Authors: Dimitar B. Iliev, Leidy Lagos, Hanna L. Thim, Sven M. Jørgensen, Aleksei Krasnov, Jorunn B. Jørgensen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
mononuclear phagocytes
antigen-presenting cells
dendritic cells
CpG oligodeoxynucleotides
Atlantic salmon
teleosts
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00378/full

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