Systematic Comparison and Rational Design of Theophylline Riboswitches for Effective Gene Repression
ABSTRACT Riboswitches are promising regulatory tools in synthetic biology. To date, 25 theophylline riboswitches have been developed for regulation of gene expression in bacteria. However, no one has systematically evaluated their regulatory effects. To promote efficient selection and application of...
Main Authors: | Xun Wang, Can Fang, Yifei Wang, Xinyu Shi, Fan Yu, Jin Xiong, Shan-Ho Chou, Jin He |
---|---|
Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2023-02-01
|
Series: | Microbiology Spectrum |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/spectrum.02752-22 |
Similar Items
-
Genetic dissection of regulation by a repressing and novel activating corrinoid riboswitch enables engineering of synthetic riboswitches
by: Rebecca R. Procknow, et al.
Published: (2023-10-01) -
Specific structural elements of the T-box riboswitch drive the two-step binding of the tRNA ligand
by: Jiacheng Zhang, et al.
Published: (2018-09-01) -
Toeholder: a software for automated design and in silico validation of toehold riboswitches
by: Angel F. Cisneros, et al.
Published: (2023-06-01) -
Characterization of the dual regulation by a c-di-GMP riboswitch Bc1 with a long expression platform from Bacillus thuringiensis
by: Lu Liu, et al.
Published: (2024-07-01) -
Bacterial riboswitches and RNA thermometers: Nature and contributions to pathogenesis
by: Jameel M. Abduljalil
Published: (2018-06-01)