EGF-induced bronchial epithelial cells drive neutrophil chemotactic and anti-apoptotic activity in asthma.

EGF-induced bronchial epithelial cells drive neutrophil chemotactic and anti-apoptotic activity in asthma.

Chronic damage and repair of the bronchial epithelium are features of asthma. We have previously reported that ex vivo stimulation of normal bronchial epithelial cells with epidermal growth factor (EGF), a key factor of epithelial repair, enhances the mechanisms of neutrophil accumulation, thereby p...

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Bibliographic Details
Main Authors: Mohib Uddin, Laurie C Lau, Grégory Seumois, Pandurangan Vijayanand, Karl J Staples, Dinesh Bagmane, Victoria Cornelius, Paul Dorinsky, Donna E Davies, Ratko Djukanović
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3770689?pdf=render

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