Pruritus in diabetes mellitus (DM) and its pathophysiology-based treatment
Pruritus is a common complaint of diabetic patients with a substantial impact on financial and health status, but the pathophysiology is unclear and treatment with antihistamines has mostly been unsuccessful. To date, we still do not have guidelines to help us treat pruritus in diabetes mellitus, so...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Universitas Gadjah Mada
2022-04-01
|
| Series: | Journal of the Medical Sciences |
| Subjects: | |
| Online Access: | https://jurnal.ugm.ac.id/bik/article/view/60487 |
| _version_ | 1797821291405770752 |
|---|---|
| author | Lorettha Wijaya Audrey Melanie Veronica Veronica Gabriela Christy |
| author_facet | Lorettha Wijaya Audrey Melanie Veronica Veronica Gabriela Christy |
| author_sort | Lorettha Wijaya |
| collection | DOAJ |
| description | Pruritus is a common complaint of diabetic patients with a substantial impact on financial and health status, but the pathophysiology is unclear and treatment with antihistamines has mostly been unsuccessful. To date, we still do not have guidelines to help us treat pruritus in diabetes mellitus, so we felt the need to review the existing literature to explore possible ways to treat these patients. We collected 85 pieces of literature from various sources such as PubMed and Google Scholar, and independently extracted these data to make this review. While the pathophysiology behind pruritus in diabetes mellitus remains largely unknown, some trials have found a few pharmacological treatments to be effective in alleviating itch in these patients. |
| first_indexed | 2024-03-13T09:51:34Z |
| format | Article |
| id | doaj.art-6847ae334de84a179be769aa8ca655bc |
| institution | Directory Open Access Journal |
| issn | 0126-1312 2356-3931 |
| language | English |
| last_indexed | 2024-03-13T09:51:34Z |
| publishDate | 2022-04-01 |
| publisher | Universitas Gadjah Mada |
| record_format | Article |
| series | Journal of the Medical Sciences |
| spelling | doaj.art-6847ae334de84a179be769aa8ca655bc2023-05-24T09:07:07ZengUniversitas Gadjah MadaJournal of the Medical Sciences0126-13122356-39312022-04-0154110.19106/JMedSci00540120221031692Pruritus in diabetes mellitus (DM) and its pathophysiology-based treatmentLorettha Wijaya0Audrey Melanie1Veronica Veronica2Gabriela Christy3Department of Dermatology and Venereology, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, IndonesiaDepartment of Dermatology and Venereology, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, IndonesiaDepartment of Dermatology and Venereology, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, IndonesiaDepartment of Dermatology and Venereology, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, IndonesiaPruritus is a common complaint of diabetic patients with a substantial impact on financial and health status, but the pathophysiology is unclear and treatment with antihistamines has mostly been unsuccessful. To date, we still do not have guidelines to help us treat pruritus in diabetes mellitus, so we felt the need to review the existing literature to explore possible ways to treat these patients. We collected 85 pieces of literature from various sources such as PubMed and Google Scholar, and independently extracted these data to make this review. While the pathophysiology behind pruritus in diabetes mellitus remains largely unknown, some trials have found a few pharmacological treatments to be effective in alleviating itch in these patients.https://jurnal.ugm.ac.id/bik/article/view/60487skin barrier disruptiondiabetic neuropathyoxidative stresschronic kidney disease-associated pruritussecond line treatment |
| spellingShingle | Lorettha Wijaya Audrey Melanie Veronica Veronica Gabriela Christy Pruritus in diabetes mellitus (DM) and its pathophysiology-based treatment Journal of the Medical Sciences skin barrier disruption diabetic neuropathy oxidative stress chronic kidney disease-associated pruritus second line treatment |
| title | Pruritus in diabetes mellitus (DM) and its pathophysiology-based treatment |
| title_full | Pruritus in diabetes mellitus (DM) and its pathophysiology-based treatment |
| title_fullStr | Pruritus in diabetes mellitus (DM) and its pathophysiology-based treatment |
| title_full_unstemmed | Pruritus in diabetes mellitus (DM) and its pathophysiology-based treatment |
| title_short | Pruritus in diabetes mellitus (DM) and its pathophysiology-based treatment |
| title_sort | pruritus in diabetes mellitus dm and its pathophysiology based treatment |
| topic | skin barrier disruption diabetic neuropathy oxidative stress chronic kidney disease-associated pruritus second line treatment |
| url | https://jurnal.ugm.ac.id/bik/article/view/60487 |
| work_keys_str_mv | AT loretthawijaya pruritusindiabetesmellitusdmanditspathophysiologybasedtreatment AT audreymelanie pruritusindiabetesmellitusdmanditspathophysiologybasedtreatment AT veronicaveronica pruritusindiabetesmellitusdmanditspathophysiologybasedtreatment AT gabrielachristy pruritusindiabetesmellitusdmanditspathophysiologybasedtreatment |