BMAL1 regulates mitochondrial fission and mitophagy through mitochondrial protein BNIP3 and is critical in the development of dilated cardiomyopathy
Abstract Dysregulation of circadian rhythms associates with cardiovascular disorders. It is known that deletion of the core circadian gene Bmal1 in mice causes dilated cardiomyopathy. However, the biological rhythm regulation system in mouse is very different from that of humans. Whether BMAL1 plays...
Main Authors: | Ermin Li, Xiuya Li, Jie Huang, Chen Xu, Qianqian Liang, Kehan Ren, Aobing Bai, Chao Lu, Ruizhe Qian, Ning Sun |
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Format: | Article |
Language: | English |
Published: |
Oxford University Press
2020-04-01
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Series: | Protein & Cell |
Subjects: | |
Online Access: | https://doi.org/10.1007/s13238-020-00713-x |
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