The Influence of Severe Plastic Deformation on Microstructure and In Vitro Biocompatibility of the New Ti-Nb-Zr-Ta-Fe-O Alloy Composition
In this work, severe plastic deformation (SPD) of the newly designed Ti-Nb-Zr-Ta-Fe-O GUM metal was successfully conducted at room temperature using high speed high pressure torsion (HSHPT) followed by cold rolling (CR) to exploit the suitability of the processed alloy for bone staples. The Ti-31.5N...
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2020-10-01
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| Online Access: | https://www.mdpi.com/1996-1944/13/21/4853 |
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| author | Carmela Gurau Gheorghe Gurau Valentina Mitran Alexandru Dan Anisoara Cimpean |
| author_facet | Carmela Gurau Gheorghe Gurau Valentina Mitran Alexandru Dan Anisoara Cimpean |
| author_sort | Carmela Gurau |
| collection | DOAJ |
| description | In this work, severe plastic deformation (SPD) of the newly designed Ti-Nb-Zr-Ta-Fe-O GUM metal was successfully conducted at room temperature using high speed high pressure torsion (HSHPT) followed by cold rolling (CR) to exploit the suitability of the processed alloy for bone staples. The Ti-31.5Nb-3.1Zr-3.1Ta-0.9Fe-0.16O GUM alloy was fabricated in a levitation melting furnace using a cold crucible and argon protective atmosphere. The as-cast specimens were subjected to SPD, specifically HSHPT, and then processed by the CR method to take the advantages of both grain refinement and larger dimensions. This approach creates the opportunity to obtain temporary orthopedic implants nanostructured by SPD. The changes induced by HSHPT technology from the coarse dendrite directly into the ultrafine grained structure were examined by optical microscopy, scanning electron microscopy and X-ray diffraction. The structural investigations showed that by increasing the deformation, a high density of grain boundaries is accumulated, leading gradually to fine grain size. In addition, the in vitro biocompatibility studies were conducted in parallel on the GUM alloy specimens in the as-cast state, and after HSHPT- and HSHPT+CR- processing. For comparative purposes, in vitro behavior of the bone-derived MC3T3-E1 cells on the commercially pure titanium has also been investigated regarding the viability and proliferation, morphology and osteogenic differentiation. The results obtained support the appropriateness of the HSHPT technology for developing compression staples able to ensure a better fixation of bone fragments. |
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| id | doaj.art-6847d943514e402986021446a853120b |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-10T15:13:54Z |
| publishDate | 2020-10-01 |
| publisher | MDPI AG |
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| series | Materials |
| spelling | doaj.art-6847d943514e402986021446a853120b2023-11-20T19:03:25ZengMDPI AGMaterials1996-19442020-10-011321485310.3390/ma13214853The Influence of Severe Plastic Deformation on Microstructure and In Vitro Biocompatibility of the New Ti-Nb-Zr-Ta-Fe-O Alloy CompositionCarmela Gurau0Gheorghe Gurau1Valentina Mitran2Alexandru Dan3Anisoara Cimpean4Faculty of Engineering, “Dunărea de Jos” University of Galati, Domnească Street 47, 800008 Galati, RomaniaFaculty of Engineering, “Dunărea de Jos” University of Galati, Domnească Street 47, 800008 Galati, RomaniaDepartment of Biochemistry and Molecular Biology, University of Bucharest, 91-95 Splaiul Independentei, 050095 Bucharest, RomaniaR&D Consultanta si Servicii, 45 Maria Ghiculeasa, 020943 Bucharest, RomaniaDepartment of Biochemistry and Molecular Biology, University of Bucharest, 91-95 Splaiul Independentei, 050095 Bucharest, RomaniaIn this work, severe plastic deformation (SPD) of the newly designed Ti-Nb-Zr-Ta-Fe-O GUM metal was successfully conducted at room temperature using high speed high pressure torsion (HSHPT) followed by cold rolling (CR) to exploit the suitability of the processed alloy for bone staples. The Ti-31.5Nb-3.1Zr-3.1Ta-0.9Fe-0.16O GUM alloy was fabricated in a levitation melting furnace using a cold crucible and argon protective atmosphere. The as-cast specimens were subjected to SPD, specifically HSHPT, and then processed by the CR method to take the advantages of both grain refinement and larger dimensions. This approach creates the opportunity to obtain temporary orthopedic implants nanostructured by SPD. The changes induced by HSHPT technology from the coarse dendrite directly into the ultrafine grained structure were examined by optical microscopy, scanning electron microscopy and X-ray diffraction. The structural investigations showed that by increasing the deformation, a high density of grain boundaries is accumulated, leading gradually to fine grain size. In addition, the in vitro biocompatibility studies were conducted in parallel on the GUM alloy specimens in the as-cast state, and after HSHPT- and HSHPT+CR- processing. For comparative purposes, in vitro behavior of the bone-derived MC3T3-E1 cells on the commercially pure titanium has also been investigated regarding the viability and proliferation, morphology and osteogenic differentiation. The results obtained support the appropriateness of the HSHPT technology for developing compression staples able to ensure a better fixation of bone fragments.https://www.mdpi.com/1996-1944/13/21/4853titanium alloyGUM metalmicrostructuresevere plastic deformationHSHPTbone staples |
| spellingShingle | Carmela Gurau Gheorghe Gurau Valentina Mitran Alexandru Dan Anisoara Cimpean The Influence of Severe Plastic Deformation on Microstructure and In Vitro Biocompatibility of the New Ti-Nb-Zr-Ta-Fe-O Alloy Composition Materials titanium alloy GUM metal microstructure severe plastic deformation HSHPT bone staples |
| title | The Influence of Severe Plastic Deformation on Microstructure and In Vitro Biocompatibility of the New Ti-Nb-Zr-Ta-Fe-O Alloy Composition |
| title_full | The Influence of Severe Plastic Deformation on Microstructure and In Vitro Biocompatibility of the New Ti-Nb-Zr-Ta-Fe-O Alloy Composition |
| title_fullStr | The Influence of Severe Plastic Deformation on Microstructure and In Vitro Biocompatibility of the New Ti-Nb-Zr-Ta-Fe-O Alloy Composition |
| title_full_unstemmed | The Influence of Severe Plastic Deformation on Microstructure and In Vitro Biocompatibility of the New Ti-Nb-Zr-Ta-Fe-O Alloy Composition |
| title_short | The Influence of Severe Plastic Deformation on Microstructure and In Vitro Biocompatibility of the New Ti-Nb-Zr-Ta-Fe-O Alloy Composition |
| title_sort | influence of severe plastic deformation on microstructure and in vitro biocompatibility of the new ti nb zr ta fe o alloy composition |
| topic | titanium alloy GUM metal microstructure severe plastic deformation HSHPT bone staples |
| url | https://www.mdpi.com/1996-1944/13/21/4853 |
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