Low-dose radiation induces unstable gene expression in developing human iPSC-derived retinal ganglion organoids

Low-dose radiation induces unstable gene expression in developing human iPSC-derived retinal ganglion organoids

Abstract The effects of low-dose radiation on undifferentiated cells carry important implications. However, the effects on developing retinal cells remain unclear. Here, we analyzed the gene expression characteristics of neuronal organoids containing immature human retinal cells under low-dose radia...

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Bibliographic Details
Main Authors: Mari Katsura, Yoshihiro Urade, Hiroko Nansai, Mika Kobayashi, Akashi Taguchi, Yukiko Ishikawa, Tomohiro Ito, Hisako Fukunaga, Hideto Tozawa, Yoko Chikaoka, Ryo Nakaki, Akinobu Echigo, Takahide Kohro, Hideko Sone, Youichiro Wada
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-40051-6

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