ATF1/miR-214-5p/ITGA7 axis promotes osteoclastogenesis to alter OVX-induced bone absorption

ATF1/miR-214-5p/ITGA7 axis promotes osteoclastogenesis to alter OVX-induced bone absorption

Abstract Background The dynamic balance of osteoblast and osteoclast is critical for bone homeostasis and overactive osteoclastic function may lead to osteoporosis. Activating transcription factor 1 (ATF1) is involved in osteoclastogenesis. However, the detailed mechanisms remain to be explored. Met...

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Bibliographic Details
Main Authors: Lu-Lin Liu, Yao-Sheng Xiao, Wei-Min Huang, Sheng Liu, Li-Xing Huang, Jing-Hua Zhong, Peng Jia, Wu-Yang Liu
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Molecular Medicine
Subjects:
ATF1
ITGA7
miR-214-5p
Osteoclastogenesis
Osteoporosis
Online Access:https://doi.org/10.1186/s10020-022-00476-7

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