Sentinel lymphatic mapping among women with early-stage cervical cancer: A systematic review
The presence of pelvic lymph node metastases is without doubt the most significant prognostic factor that determines recurrences and survival of women with early-stage cervical cancer. To avoid the underdiagnosis of lymph node metastasis, pelvic lymphadenectomy procedure is routinely performed with...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2018-10-01
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| Series: | Taiwanese Journal of Obstetrics & Gynecology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1028455918301712 |
| _version_ | 1811198173255827456 |
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| author | Jerry Cheng-Yen Lai Kuan-Ju Lai Edward Yi-Yung Yu Sho-Ting Hung Chia-Ying Chu Kung-Liahng Wang |
| author_facet | Jerry Cheng-Yen Lai Kuan-Ju Lai Edward Yi-Yung Yu Sho-Ting Hung Chia-Ying Chu Kung-Liahng Wang |
| author_sort | Jerry Cheng-Yen Lai |
| collection | DOAJ |
| description | The presence of pelvic lymph node metastases is without doubt the most significant prognostic factor that determines recurrences and survival of women with early-stage cervical cancer. To avoid the underdiagnosis of lymph node metastasis, pelvic lymphadenectomy procedure is routinely performed with radical hysterectomy procedure. However, the pelvic lymphadenectomy procedure may not be necessary in most of these women due to the relatively low incidence of pelvic lymph node metastasis. The removal of large numbers of pelvic lymph nodes could also render non-metastatic irreversible damages for these women, including vessel, nerve, or ureteral injuries; formation of lymphocysts; and lymphedema. Over the past decades, the concept of sentinel lymph node biopsy has emerged as a popular and widespread surgical technique for the evaluation of the pelvic lymph node status in gynecologic malignancies. The histological status of sentinel lymph node should be representative for all other lymph nodes in the regional drainage area. If metastasis is non-existent in the sentinel lymph node, the likelihood of metastatic spread in the remaining regional lymph nodes is very low. Further lymphadenectomy is therefore not necessary for a patient with negative sentinel lymph nodes. Since the uterine cervix has several lymphatic drainage pathways, it is a challenging task to assess the distribution pattern of sentinel lymph nodes in women with early-stage cervical cancer. This review article will adapt the methodology proposed in these studies to systematically review sentinel lymphatic mapping among women with early-stage cervical cancer. Keywords: Cervical cancer, Lymphadenectomy, Sentinel lymph node |
| first_indexed | 2024-04-12T01:26:21Z |
| format | Article |
| id | doaj.art-684beb2ab16044039e915aefc74c0c25 |
| institution | Directory Open Access Journal |
| issn | 1028-4559 |
| language | English |
| last_indexed | 2024-04-12T01:26:21Z |
| publishDate | 2018-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Taiwanese Journal of Obstetrics & Gynecology |
| spelling | doaj.art-684beb2ab16044039e915aefc74c0c252022-12-22T03:53:38ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592018-10-01575636643Sentinel lymphatic mapping among women with early-stage cervical cancer: A systematic reviewJerry Cheng-Yen Lai0Kuan-Ju Lai1Edward Yi-Yung Yu2Sho-Ting Hung3Chia-Ying Chu4Kung-Liahng Wang5Department of Medical Research, Taitung MacKay Memorial Hospital, Taitung, TaiwanDepartment of Pathology, Taitung MacKay Memorial Hospital, Taitung, TaiwanDepartment of Radiology, Taitung MacKay Memorial Hospital, Taitung, TaiwanDepartment of Radiology, Taitung MacKay Memorial Hospital, Taitung, TaiwanDepartment of Pathology, Taitung MacKay Memorial Hospital, Taitung, TaiwanDepartment of Obstetrics and Gynecology, MacKay Memorial Hospital, Taipei, Taiwan; Department of Nursing, MacKay Junior College of Medicine, Nursing, and Management, Taipei, Taiwan; Department of Obstetrics and Gynecology, Taitung MacKay Memorial Hospital, Taitung, Taiwan; Department of Obstetrics and Gynecology, MacKay Medical College, New Taipei City, Taiwan; Corresponding author. Taitung MacKay Memorial Hospital, No.1, Lane 303, Changsha Street, Taitung City 950, Taiwan. Fax: +886 89 321240.The presence of pelvic lymph node metastases is without doubt the most significant prognostic factor that determines recurrences and survival of women with early-stage cervical cancer. To avoid the underdiagnosis of lymph node metastasis, pelvic lymphadenectomy procedure is routinely performed with radical hysterectomy procedure. However, the pelvic lymphadenectomy procedure may not be necessary in most of these women due to the relatively low incidence of pelvic lymph node metastasis. The removal of large numbers of pelvic lymph nodes could also render non-metastatic irreversible damages for these women, including vessel, nerve, or ureteral injuries; formation of lymphocysts; and lymphedema. Over the past decades, the concept of sentinel lymph node biopsy has emerged as a popular and widespread surgical technique for the evaluation of the pelvic lymph node status in gynecologic malignancies. The histological status of sentinel lymph node should be representative for all other lymph nodes in the regional drainage area. If metastasis is non-existent in the sentinel lymph node, the likelihood of metastatic spread in the remaining regional lymph nodes is very low. Further lymphadenectomy is therefore not necessary for a patient with negative sentinel lymph nodes. Since the uterine cervix has several lymphatic drainage pathways, it is a challenging task to assess the distribution pattern of sentinel lymph nodes in women with early-stage cervical cancer. This review article will adapt the methodology proposed in these studies to systematically review sentinel lymphatic mapping among women with early-stage cervical cancer. Keywords: Cervical cancer, Lymphadenectomy, Sentinel lymph nodehttp://www.sciencedirect.com/science/article/pii/S1028455918301712 |
| spellingShingle | Jerry Cheng-Yen Lai Kuan-Ju Lai Edward Yi-Yung Yu Sho-Ting Hung Chia-Ying Chu Kung-Liahng Wang Sentinel lymphatic mapping among women with early-stage cervical cancer: A systematic review Taiwanese Journal of Obstetrics & Gynecology |
| title | Sentinel lymphatic mapping among women with early-stage cervical cancer: A systematic review |
| title_full | Sentinel lymphatic mapping among women with early-stage cervical cancer: A systematic review |
| title_fullStr | Sentinel lymphatic mapping among women with early-stage cervical cancer: A systematic review |
| title_full_unstemmed | Sentinel lymphatic mapping among women with early-stage cervical cancer: A systematic review |
| title_short | Sentinel lymphatic mapping among women with early-stage cervical cancer: A systematic review |
| title_sort | sentinel lymphatic mapping among women with early stage cervical cancer a systematic review |
| url | http://www.sciencedirect.com/science/article/pii/S1028455918301712 |
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