A Novel Role for Programmed Cell Death Receptor Ligand-1 in Sepsis-Induced Intestinal Dysfunction
Abstract Studies imply that intestinal barrier dysfunction is a key contributor to morbid events associated with sepsis. Recently, the co-inhibitory molecule programmed death-ligand1 (PD-L1) has been shown to be involved in the regulation of intestinal immune tolerance and/or inflammation. Our previ...
Main Authors: | Youping Wu, Chun-Shiang Chung, Yaping Chen, Sean Farrell Monaghan, Sima Patel, Xin Huang, Daithi Seamus Heffernan, Alfred Ayala |
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Format: | Article |
Language: | English |
Published: |
BMC
2016-10-01
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Series: | Molecular Medicine |
Online Access: | http://link.springer.com/article/10.2119/molmed.2016.00150 |
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