Nostochopcerol, a new antibacterial monoacylglycerol from the edible cyanobacterium Nostochopsis lobatus

A new antibacterial 3-monoacyl-sn-glycerol, nostochopcerol (1), was isolated from a cultured algal mass of the edible cyanobacterium Nostochopsis lobatus MAC0804NAN. The structure of compound 1 was established by the analysis of NMR and MS data while its chirality was established by comparison of op...

Full description

Bibliographic Details
Main Authors: Naoya Oku, Saki Hayashi, Yuji Yamaguchi, Hiroyuki Takenaka, Yasuhiro Igarashi
Format: Article
Language:English
Published: Beilstein-Institut 2023-02-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.19.13
_version_ 1811158665033416704
author Naoya Oku
Saki Hayashi
Yuji Yamaguchi
Hiroyuki Takenaka
Yasuhiro Igarashi
author_facet Naoya Oku
Saki Hayashi
Yuji Yamaguchi
Hiroyuki Takenaka
Yasuhiro Igarashi
author_sort Naoya Oku
collection DOAJ
description A new antibacterial 3-monoacyl-sn-glycerol, nostochopcerol (1), was isolated from a cultured algal mass of the edible cyanobacterium Nostochopsis lobatus MAC0804NAN. The structure of compound 1 was established by the analysis of NMR and MS data while its chirality was established by comparison of optical rotation values with synthetically prepared authentics. Compound 1 inhibited the growth of Bacillus subtilis and Staphylococcus aureus at MIC of 50 μg/mL and 100 μg/mL, respectively.
first_indexed 2024-04-10T05:26:55Z
format Article
id doaj.art-685544acabb04460952f207a289bc1be
institution Directory Open Access Journal
issn 1860-5397
language English
last_indexed 2024-04-10T05:26:55Z
publishDate 2023-02-01
publisher Beilstein-Institut
record_format Article
series Beilstein Journal of Organic Chemistry
spelling doaj.art-685544acabb04460952f207a289bc1be2023-03-07T13:31:31ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972023-02-0119113313810.3762/bjoc.19.131860-5397-19-13Nostochopcerol, a new antibacterial monoacylglycerol from the edible cyanobacterium Nostochopsis lobatusNaoya Oku0Saki Hayashi1Yuji Yamaguchi2Hiroyuki Takenaka3Yasuhiro Igarashi4Biotechnology Research Center and Department of Biotechnology, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama 939-0398, Japan Biotechnology Research Center and Department of Biotechnology, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama 939-0398, Japan MAC Gifu Research Institute, MicroAlgae Corporation, 4-15 Akebono, Gifu 500-8148, JapanMAC Gifu Research Institute, MicroAlgae Corporation, 4-15 Akebono, Gifu 500-8148, JapanBiotechnology Research Center and Department of Biotechnology, Toyama Prefectural University, 5180 Kurokawa, Imizu, Toyama 939-0398, Japan A new antibacterial 3-monoacyl-sn-glycerol, nostochopcerol (1), was isolated from a cultured algal mass of the edible cyanobacterium Nostochopsis lobatus MAC0804NAN. The structure of compound 1 was established by the analysis of NMR and MS data while its chirality was established by comparison of optical rotation values with synthetically prepared authentics. Compound 1 inhibited the growth of Bacillus subtilis and Staphylococcus aureus at MIC of 50 μg/mL and 100 μg/mL, respectively.https://doi.org/10.3762/bjoc.19.13antibacterialcyanobacteriumediblemonoacylglycerolnostochopsis lobatus
spellingShingle Naoya Oku
Saki Hayashi
Yuji Yamaguchi
Hiroyuki Takenaka
Yasuhiro Igarashi
Nostochopcerol, a new antibacterial monoacylglycerol from the edible cyanobacterium Nostochopsis lobatus
Beilstein Journal of Organic Chemistry
antibacterial
cyanobacterium
edible
monoacylglycerol
nostochopsis lobatus
title Nostochopcerol, a new antibacterial monoacylglycerol from the edible cyanobacterium Nostochopsis lobatus
title_full Nostochopcerol, a new antibacterial monoacylglycerol from the edible cyanobacterium Nostochopsis lobatus
title_fullStr Nostochopcerol, a new antibacterial monoacylglycerol from the edible cyanobacterium Nostochopsis lobatus
title_full_unstemmed Nostochopcerol, a new antibacterial monoacylglycerol from the edible cyanobacterium Nostochopsis lobatus
title_short Nostochopcerol, a new antibacterial monoacylglycerol from the edible cyanobacterium Nostochopsis lobatus
title_sort nostochopcerol a new antibacterial monoacylglycerol from the edible cyanobacterium nostochopsis lobatus
topic antibacterial
cyanobacterium
edible
monoacylglycerol
nostochopsis lobatus
url https://doi.org/10.3762/bjoc.19.13
work_keys_str_mv AT naoyaoku nostochopcerolanewantibacterialmonoacylglycerolfromtheediblecyanobacteriumnostochopsislobatus
AT sakihayashi nostochopcerolanewantibacterialmonoacylglycerolfromtheediblecyanobacteriumnostochopsislobatus
AT yujiyamaguchi nostochopcerolanewantibacterialmonoacylglycerolfromtheediblecyanobacteriumnostochopsislobatus
AT hiroyukitakenaka nostochopcerolanewantibacterialmonoacylglycerolfromtheediblecyanobacteriumnostochopsislobatus
AT yasuhiroigarashi nostochopcerolanewantibacterialmonoacylglycerolfromtheediblecyanobacteriumnostochopsislobatus