Conjunctival structure of glaucomatous eyes treated with anti-glaucoma eye drops: a cross-sectional study using anterior segment optical coherence tomography
Abstract Background To determine the effect of various factors to the preservation rate of the conjunctival layer borderlines of glaucomatous eyes treated with anti-glaucoma eye drops. Methods Anterior segment optical coherence tomography (AS-OCT) images of the bulbar conjunctiva of 328 eyes were an...
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| Format: | Article |
| Language: | English |
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BMC
2020-06-01
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| Series: | BMC Ophthalmology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12886-020-01518-6 |
| _version_ | 1819205970916540416 |
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| author | Makoto Gozawa Yoshihiro Takamura Kentaro Iwasaki Shogo Arimura Masaru Inatani |
| author_facet | Makoto Gozawa Yoshihiro Takamura Kentaro Iwasaki Shogo Arimura Masaru Inatani |
| author_sort | Makoto Gozawa |
| collection | DOAJ |
| description | Abstract Background To determine the effect of various factors to the preservation rate of the conjunctival layer borderlines of glaucomatous eyes treated with anti-glaucoma eye drops. Methods Anterior segment optical coherence tomography (AS-OCT) images of the bulbar conjunctiva of 328 eyes were analyzed with and without anti-glaucoma eye drops to quantify the preservation rates of the conjunctival layer borderlines. Results More anti-glaucoma eye drops and a longer duration of administration were associated with lower preservation rates of the borderlines between both the conjunctival stroma/Tenon’s capsule (P < 0.001 and P < 0.001, respectively) and Tenon’s capsule/sclera (P < 0.001 and P < 0.001, respectively). Prostaglandin analogs and fixed combinations of β-blockers/prostaglandin analogs were prognostic factors for lower preservation rates of the borderlines between both the conjunctival stroma/Tenon’s capsule (P < 0.001 and P = 0.009, respectively) and Tenon’s capsule/sclera (P < 0.001 and P = 0.008, respectively). Conclusions Numerous anti-glaucoma eye drops and their long-term administration are associated with the disruption of the bulbar conjunctival borderlines detected by AS-OCT. |
| first_indexed | 2024-12-23T05:00:10Z |
| format | Article |
| id | doaj.art-6856880c905a4fdd9ab5f69eaaa8a8ff |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-12-23T05:00:10Z |
| publishDate | 2020-06-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj.art-6856880c905a4fdd9ab5f69eaaa8a8ff2022-12-21T17:59:15ZengBMCBMC Ophthalmology1471-24152020-06-012011710.1186/s12886-020-01518-6Conjunctival structure of glaucomatous eyes treated with anti-glaucoma eye drops: a cross-sectional study using anterior segment optical coherence tomographyMakoto Gozawa0Yoshihiro Takamura1Kentaro Iwasaki2Shogo Arimura3Masaru Inatani4Department of Ophthalmology, Faculty of Medical Sciences, University of FukuiDepartment of Ophthalmology, Faculty of Medical Sciences, University of FukuiDepartment of Ophthalmology, Faculty of Medical Sciences, University of FukuiDepartment of Ophthalmology, Faculty of Medical Sciences, University of FukuiDepartment of Ophthalmology, Faculty of Medical Sciences, University of FukuiAbstract Background To determine the effect of various factors to the preservation rate of the conjunctival layer borderlines of glaucomatous eyes treated with anti-glaucoma eye drops. Methods Anterior segment optical coherence tomography (AS-OCT) images of the bulbar conjunctiva of 328 eyes were analyzed with and without anti-glaucoma eye drops to quantify the preservation rates of the conjunctival layer borderlines. Results More anti-glaucoma eye drops and a longer duration of administration were associated with lower preservation rates of the borderlines between both the conjunctival stroma/Tenon’s capsule (P < 0.001 and P < 0.001, respectively) and Tenon’s capsule/sclera (P < 0.001 and P < 0.001, respectively). Prostaglandin analogs and fixed combinations of β-blockers/prostaglandin analogs were prognostic factors for lower preservation rates of the borderlines between both the conjunctival stroma/Tenon’s capsule (P < 0.001 and P = 0.009, respectively) and Tenon’s capsule/sclera (P < 0.001 and P = 0.008, respectively). Conclusions Numerous anti-glaucoma eye drops and their long-term administration are associated with the disruption of the bulbar conjunctival borderlines detected by AS-OCT.http://link.springer.com/article/10.1186/s12886-020-01518-6GlaucomaConjunctivaAnterior segment optical coherence tomographyAnti-glaucoma eye drops |
| spellingShingle | Makoto Gozawa Yoshihiro Takamura Kentaro Iwasaki Shogo Arimura Masaru Inatani Conjunctival structure of glaucomatous eyes treated with anti-glaucoma eye drops: a cross-sectional study using anterior segment optical coherence tomography BMC Ophthalmology Glaucoma Conjunctiva Anterior segment optical coherence tomography Anti-glaucoma eye drops |
| title | Conjunctival structure of glaucomatous eyes treated with anti-glaucoma eye drops: a cross-sectional study using anterior segment optical coherence tomography |
| title_full | Conjunctival structure of glaucomatous eyes treated with anti-glaucoma eye drops: a cross-sectional study using anterior segment optical coherence tomography |
| title_fullStr | Conjunctival structure of glaucomatous eyes treated with anti-glaucoma eye drops: a cross-sectional study using anterior segment optical coherence tomography |
| title_full_unstemmed | Conjunctival structure of glaucomatous eyes treated with anti-glaucoma eye drops: a cross-sectional study using anterior segment optical coherence tomography |
| title_short | Conjunctival structure of glaucomatous eyes treated with anti-glaucoma eye drops: a cross-sectional study using anterior segment optical coherence tomography |
| title_sort | conjunctival structure of glaucomatous eyes treated with anti glaucoma eye drops a cross sectional study using anterior segment optical coherence tomography |
| topic | Glaucoma Conjunctiva Anterior segment optical coherence tomography Anti-glaucoma eye drops |
| url | http://link.springer.com/article/10.1186/s12886-020-01518-6 |
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