Improvement of indirect immunofluorescence technique to detect antineutrophil cytoplasmic antibodies and its impact on test positivity rate

Improvement of indirect immunofluorescence technique to detect antineutrophil cytoplasmic antibodies and its impact on test positivity rate

The indirect immunofluorescence (IIF) technique for antineutrophil cytoplasmic antibodies (ANCA) detection is subject to substantial differences across laboratories. This study aimed to assess the impact of improvements in the IIF-ANCA technique on the positivity rate of ANCA tests. A cross-sectiona...

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Bibliographic Details
Main Authors: E.B. Zarur, S.H. Rodrigues, O. Ambrogini Jr, M.L.G. Ferraz, G. Mastroianni-Kirsztajn, L.E.C. Andrade, A.W.S. de Souza
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2023-07-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Antineutrophil cytoplasmic antibodies
ANCA-associated vasculitis
Autoimmune hepatitis
Ulcerative colitis
PR3-ANCA
MPO-ANCA
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2023000100647&tlng=en

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