Social anxiety disorder in an adolescent with agenesis of the corpus callosum: a case report

Abstract Background The agenesis of corpus callosum (ACC) could impair the connectivity of the hemispheres of the cerebral cortex and cause cognitive impairments, social and behavioral issues, and even psychiatric disorders. Although social deficits are common in ACC patients, it is rare for a socia...

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Main Authors: Runnan Yang, Yuan Cao, Danmei He, Wen Dang, Changjian Qiu, Wei Zhang
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Psychiatry
Subjects:
Online Access:https://doi.org/10.1186/s12888-022-04332-0
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author Runnan Yang
Yuan Cao
Danmei He
Wen Dang
Changjian Qiu
Wei Zhang
author_facet Runnan Yang
Yuan Cao
Danmei He
Wen Dang
Changjian Qiu
Wei Zhang
author_sort Runnan Yang
collection DOAJ
description Abstract Background The agenesis of corpus callosum (ACC) could impair the connectivity of the hemispheres of the cerebral cortex and cause cognitive impairments, social and behavioral issues, and even psychiatric disorders. Although social deficits are common in ACC patients, it is rare for a social anxiety disorder to occur. Case presentation To report a 17-year-old adolescent with complete ACC associated with social anxiety disorder, depression, impulsive behavior, and other neurodevelopmental defects such as intellectual disabilities. His avoidance and fear were improved after treatment with sertraline. Conclusions This is the first report of social anxiety disorder in ACC patients. The possible relationship between brain structural abnormities and anxiety syndrome should be investigated in more studies.
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spelling doaj.art-685af45f600546e99e2a047e85bd66bc2022-12-22T02:46:23ZengBMCBMC Psychiatry1471-244X2022-11-012211610.1186/s12888-022-04332-0Social anxiety disorder in an adolescent with agenesis of the corpus callosum: a case reportRunnan Yang0Yuan Cao1Danmei He2Wen Dang3Changjian Qiu4Wei Zhang5Mental Health Center, West China Hospital, Sichuan UniversityDepartment of Nuclear Medicine, West China Hospital, Sichuan UniversityWest China Biomedical Big Data Center, West China Hospital, Sichuan UniversityWest China Biomedical Big Data Center, West China Hospital, Sichuan UniversityMental Health Center, West China Hospital, Sichuan UniversityMental Health Center, West China Hospital, Sichuan UniversityAbstract Background The agenesis of corpus callosum (ACC) could impair the connectivity of the hemispheres of the cerebral cortex and cause cognitive impairments, social and behavioral issues, and even psychiatric disorders. Although social deficits are common in ACC patients, it is rare for a social anxiety disorder to occur. Case presentation To report a 17-year-old adolescent with complete ACC associated with social anxiety disorder, depression, impulsive behavior, and other neurodevelopmental defects such as intellectual disabilities. His avoidance and fear were improved after treatment with sertraline. Conclusions This is the first report of social anxiety disorder in ACC patients. The possible relationship between brain structural abnormities and anxiety syndrome should be investigated in more studies.https://doi.org/10.1186/s12888-022-04332-0Agenesis of the corpus callosumSocial anxiety disorderSocial phobiaPsychiatric disordersCase report
spellingShingle Runnan Yang
Yuan Cao
Danmei He
Wen Dang
Changjian Qiu
Wei Zhang
Social anxiety disorder in an adolescent with agenesis of the corpus callosum: a case report
BMC Psychiatry
Agenesis of the corpus callosum
Social anxiety disorder
Social phobia
Psychiatric disorders
Case report
title Social anxiety disorder in an adolescent with agenesis of the corpus callosum: a case report
title_full Social anxiety disorder in an adolescent with agenesis of the corpus callosum: a case report
title_fullStr Social anxiety disorder in an adolescent with agenesis of the corpus callosum: a case report
title_full_unstemmed Social anxiety disorder in an adolescent with agenesis of the corpus callosum: a case report
title_short Social anxiety disorder in an adolescent with agenesis of the corpus callosum: a case report
title_sort social anxiety disorder in an adolescent with agenesis of the corpus callosum a case report
topic Agenesis of the corpus callosum
Social anxiety disorder
Social phobia
Psychiatric disorders
Case report
url https://doi.org/10.1186/s12888-022-04332-0
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