Intranasal Vaccine Delivery Technology for Respiratory Tract Disease Application with a Special Emphasis on Pneumococcal Disease

This mini-review will cover recent trends in intranasal (IN) vaccine delivery as it relates to applications for respiratory tract diseases. The logic and rationale for IN vaccine delivery will be compared to methods and applications accompanying this particular administration route. In addition, we...

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Main Authors: William Walkowski, Justin Bassett, Manmeet Bhalla, Blaine A. Pfeifer, Elsa N. Bou Ghanem
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/9/6/589
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author William Walkowski
Justin Bassett
Manmeet Bhalla
Blaine A. Pfeifer
Elsa N. Bou Ghanem
author_facet William Walkowski
Justin Bassett
Manmeet Bhalla
Blaine A. Pfeifer
Elsa N. Bou Ghanem
author_sort William Walkowski
collection DOAJ
description This mini-review will cover recent trends in intranasal (IN) vaccine delivery as it relates to applications for respiratory tract diseases. The logic and rationale for IN vaccine delivery will be compared to methods and applications accompanying this particular administration route. In addition, we will focus extended discussion on the potential role of IN vaccination in the context of respiratory tract diseases, with a special emphasis on pneumococcal disease. Here, elements of this disease, including its prevalence and impact upon the elderly population, will be viewed from the standpoint of improving health outcomes through vaccine design and delivery technology and how IN administration can play a role in such efforts.
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spelling doaj.art-685cc7a50674412f8e029fcbe211af582023-11-21T22:30:24ZengMDPI AGVaccines2076-393X2021-06-019658910.3390/vaccines9060589Intranasal Vaccine Delivery Technology for Respiratory Tract Disease Application with a Special Emphasis on Pneumococcal DiseaseWilliam Walkowski0Justin Bassett1Manmeet Bhalla2Blaine A. Pfeifer3Elsa N. Bou Ghanem4Department of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14260, USADepartment of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14260, USADepartment of Microbiology and Immunology, University at Buffalo, The State University of New York, Buffalo, NY 14203, USADepartment of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14260, USADepartment of Microbiology and Immunology, University at Buffalo, The State University of New York, Buffalo, NY 14203, USAThis mini-review will cover recent trends in intranasal (IN) vaccine delivery as it relates to applications for respiratory tract diseases. The logic and rationale for IN vaccine delivery will be compared to methods and applications accompanying this particular administration route. In addition, we will focus extended discussion on the potential role of IN vaccination in the context of respiratory tract diseases, with a special emphasis on pneumococcal disease. Here, elements of this disease, including its prevalence and impact upon the elderly population, will be viewed from the standpoint of improving health outcomes through vaccine design and delivery technology and how IN administration can play a role in such efforts.https://www.mdpi.com/2076-393X/9/6/589intranasalpulmonaryrespiratory tractvaccinepneumococcal diseaseaging
spellingShingle William Walkowski
Justin Bassett
Manmeet Bhalla
Blaine A. Pfeifer
Elsa N. Bou Ghanem
Intranasal Vaccine Delivery Technology for Respiratory Tract Disease Application with a Special Emphasis on Pneumococcal Disease
Vaccines
intranasal
pulmonary
respiratory tract
vaccine
pneumococcal disease
aging
title Intranasal Vaccine Delivery Technology for Respiratory Tract Disease Application with a Special Emphasis on Pneumococcal Disease
title_full Intranasal Vaccine Delivery Technology for Respiratory Tract Disease Application with a Special Emphasis on Pneumococcal Disease
title_fullStr Intranasal Vaccine Delivery Technology for Respiratory Tract Disease Application with a Special Emphasis on Pneumococcal Disease
title_full_unstemmed Intranasal Vaccine Delivery Technology for Respiratory Tract Disease Application with a Special Emphasis on Pneumococcal Disease
title_short Intranasal Vaccine Delivery Technology for Respiratory Tract Disease Application with a Special Emphasis on Pneumococcal Disease
title_sort intranasal vaccine delivery technology for respiratory tract disease application with a special emphasis on pneumococcal disease
topic intranasal
pulmonary
respiratory tract
vaccine
pneumococcal disease
aging
url https://www.mdpi.com/2076-393X/9/6/589
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