Clinical implications of serum N‐glycan profiling as a diagnostic and prognostic biomarker in germ‐cell tumors

Clinical implications of serum N‐glycan profiling as a diagnostic and prognostic biomarker in germ‐cell tumors

Abstract Serum biomarker monitoring is essential for management of germ‐cell tumors (GCT). However, not all GCT are positive for conventional tumor markers. We examined whether serum N‐glycan‐based biomarkers can be applied for detection and prognosis in patients with GCT. We performed a comprehensi...

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Bibliographic Details
Main Authors: Takuma Narita, Shingo Hatakeyama, Tohru Yoneyama, Shintaro Narita, Shinichi Yamashita, Koji Mitsuzuka, Toshihiko Sakurai, Sadafumi Kawamura, Tatsuo Tochigi, Ippei Takahashi, Shigeyuki Nakaji, Yuki Tobisawa, Hayato Yamamoto, Takuya Koie, Norihiko Tsuchiya, Tomonori Habuchi, Yoichi Arai, Chikara Ohyama
Format: Article
Language:English
Published: Wiley 2017-04-01
Series:Cancer Medicine
Subjects:
Biomarker
germ‐cell tumors
glycoblotting
mass spectrometry
serum N‐glycan
Online Access:https://doi.org/10.1002/cam4.1035

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