Exploring the molecular mechanism of Gan Shuang granules for the treatment of non-alcoholic steatohepatitis using network pharmacology, molecular docking, and experimental verification

Exploring the molecular mechanism of Gan Shuang granules for the treatment of non-alcoholic steatohepatitis using network pharmacology, molecular docking, and experimental verification

Background: With the gradual increase in prevalence in recent years, non-alcoholic steatohepatitis (NASH) has become one of the significant health problems that urgently needs to be addressed worldwide. GanShuang Granules (GSG) is derived from the classical Chinese formula Xiaoyao San and mainly use...

Full description

Bibliographic Details
Main Authors: Guoguo Zhi, Bingjie Shao, Tianyan Zheng, Jie Mu, Jingwei Li, Yiyuan Feng, Sha Zhu, Yanni Dang, Feng Liu, Dong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Pharmacology
Subjects:
GSG
NAFLD/NASH
UHPLC-Q/Orbitrap-MS/MS
network pharmacology
molecular docking
molecular mechanism
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1082451/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1082451/full

Similar Items