The Toll-Like Receptor 5 Agonist Entolimod Mitigates Lethal Acute Radiation Syndrome in Non-Human Primates.

The Toll-Like Receptor 5 Agonist Entolimod Mitigates Lethal Acute Radiation Syndrome in Non-Human Primates.

There are currently no approved medical radiation countermeasures (MRC) to reduce the lethality of high-dose total body ionizing irradiation expected in nuclear emergencies. An ideal MRC would be effective even when administered well after radiation exposure and would counteract the effects of irrad...

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Main Authors: Vadim I Krivokrysenko, Ilia A Toshkov, Anatoli S Gleiberman, Peter Krasnov, Inna Shyshynova, Ivan Bespalov, Ratan K Maitra, Natalya V Narizhneva, Vijay K Singh, Mark H Whitnall, Andrei A Purmal, Alexander N Shakhov, Andrei V Gudkov, Elena Feinstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4569586?pdf=render

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