Isolation and identification of kaempferol from jangkang (Homalocladium platycladum (F. Muell) Bailey) leaves and its antibacterial activity
Isolation and identification of kaempferol from jangkang (Homalocladium platycladum (F. Muell) Bailey) leaves and its activity against B. subtilis ATCC 9466 dan S. typhi ATCC 1408 has been done. The dried ground leaves (300.04 gram) were macerated with petroleum ether, chlorofor...
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Format: | Article |
Language: | English |
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Universitas Gadjah Mada
2011-01-01
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Series: | Indonesian Journal of Pharmacy |
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Online Access: | http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/481/360 |
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author | Maulita Cut Nuria Wahyono Ratna Asmah Susidarti |
author_facet | Maulita Cut Nuria Wahyono Ratna Asmah Susidarti |
author_sort | Maulita Cut Nuria |
collection | DOAJ |
description | Isolation and identification of kaempferol from jangkang (Homalocladium platycladum (F. Muell) Bailey) leaves and its activity against B. subtilis ATCC 9466 dan S. typhi ATCC 1408 has been done. The dried ground leaves (300.04 gram) were macerated with petroleum ether, chloroform and methanol respectively. The methanol extract was the most active extract against both bacteria. Further separations of this extract using preparative thin layer chromatography yielded flavonoid glycoside. Its aglicon was identified as kaempferol based on its spectroscopic data (MS, IR, and UV-Vis) and UV spectrum (densitometry). This compound shows iradical zone of 6.62 mm (Bacillus subtilis) and 6.27 mm (Salmonella typhi) at concentration of 200 µg/disk. |
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institution | Directory Open Access Journal |
issn | 2338-9427 2338-9486 |
language | English |
last_indexed | 2024-12-24T03:33:20Z |
publishDate | 2011-01-01 |
publisher | Universitas Gadjah Mada |
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series | Indonesian Journal of Pharmacy |
spelling | doaj.art-6866744bfd86458d9b78390faa3e48412022-12-21T17:17:08ZengUniversitas Gadjah MadaIndonesian Journal of Pharmacy2338-94272338-94862011-01-0122118Isolation and identification of kaempferol from jangkang (Homalocladium platycladum (F. Muell) Bailey) leaves and its antibacterial activityMaulita Cut Nuria0Wahyono1Ratna Asmah Susidarti2Fakultas Farmasi, Universitas Wahid Hasyim SemarangFakultas Farmasi, Universitas Gadjah Mada JogjakartaFakultas Farmasi, Universitas Gadjah Mada JogjakartaIsolation and identification of kaempferol from jangkang (Homalocladium platycladum (F. Muell) Bailey) leaves and its activity against B. subtilis ATCC 9466 dan S. typhi ATCC 1408 has been done. The dried ground leaves (300.04 gram) were macerated with petroleum ether, chloroform and methanol respectively. The methanol extract was the most active extract against both bacteria. Further separations of this extract using preparative thin layer chromatography yielded flavonoid glycoside. Its aglicon was identified as kaempferol based on its spectroscopic data (MS, IR, and UV-Vis) and UV spectrum (densitometry). This compound shows iradical zone of 6.62 mm (Bacillus subtilis) and 6.27 mm (Salmonella typhi) at concentration of 200 µg/disk.http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/481/360kaempferoljangkangglycosideaglicon |
spellingShingle | Maulita Cut Nuria Wahyono Ratna Asmah Susidarti Isolation and identification of kaempferol from jangkang (Homalocladium platycladum (F. Muell) Bailey) leaves and its antibacterial activity Indonesian Journal of Pharmacy kaempferol jangkang glycoside aglicon |
title | Isolation and identification of kaempferol from jangkang (Homalocladium platycladum (F. Muell) Bailey) leaves and its antibacterial activity |
title_full | Isolation and identification of kaempferol from jangkang (Homalocladium platycladum (F. Muell) Bailey) leaves and its antibacterial activity |
title_fullStr | Isolation and identification of kaempferol from jangkang (Homalocladium platycladum (F. Muell) Bailey) leaves and its antibacterial activity |
title_full_unstemmed | Isolation and identification of kaempferol from jangkang (Homalocladium platycladum (F. Muell) Bailey) leaves and its antibacterial activity |
title_short | Isolation and identification of kaempferol from jangkang (Homalocladium platycladum (F. Muell) Bailey) leaves and its antibacterial activity |
title_sort | isolation and identification of kaempferol from jangkang homalocladium platycladum f muell bailey leaves and its antibacterial activity |
topic | kaempferol jangkang glycoside aglicon |
url | http://indonesianjpharm.farmasi.ugm.ac.id/index.php/3/article/view/481/360 |
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