Epidemiological scenario of Q fever hospitalized patients in the Spanish Health System: What’s new
Objectives: The objective of this study was to assess the epidemiology and burden of Q fever (QF) in Spain. Methods: We designed a retrospective descriptive study using the minimum basic data set in patients admitted to hospitals of the National Health System between 1998 and 2015 with a diagnosis o...
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| Format: | Article |
| Language: | English |
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Elsevier
2020-01-01
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| Series: | International Journal of Infectious Diseases |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971219304370 |
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| author | Beatriz Rodríguez-Alonso Hugo Almeida Montserrat Alonso-Sardón Amparo López-Bernus Javier Pardo-Lledias Virginia Velasco-Tirado Cristina Carranza-Rodríguez José Luis Pérez-Arellano Moncef Belhassen-García |
| author_facet | Beatriz Rodríguez-Alonso Hugo Almeida Montserrat Alonso-Sardón Amparo López-Bernus Javier Pardo-Lledias Virginia Velasco-Tirado Cristina Carranza-Rodríguez José Luis Pérez-Arellano Moncef Belhassen-García |
| author_sort | Beatriz Rodríguez-Alonso |
| collection | DOAJ |
| description | Objectives: The objective of this study was to assess the epidemiology and burden of Q fever (QF) in Spain. Methods: We designed a retrospective descriptive study using the minimum basic data set in patients admitted to hospitals of the National Health System between 1998 and 2015 with a diagnosis of Q fever (ICD-9: 083.0.). Results: We found 4214 hospitalized patients with a mean age (±SD) of 50.9 ± 19.3 years. The male/female ratio was 3:1. The incidence rate was between 0.41 and 0.65 cases per 100,000 person-years over the 18-year period. The highest incidence of cases was from March to August (p = 0.024). 21.1% patients had pneumonia, 17.5% had liver disease, and only 3.2% had endocarditis. The average hospital stay was 13.8 days (±12.8). A total of 117 (2.8%) patients died. The total mean cost of QF is approximately €154,232,779 (€36,600 ± 139,422 per patient). Conclusions: QF is an important zoonosis in Spain with a stable incidence rate and high cost for hospitalization. Older patients have a more severe clinical picture and higher mortality, which can be decreased with early clinical suspicion. Keywords: Q fever, Coxiella burnetii, Zoonosis, Pneumonia, Hepatitis, Epidemiology |
| first_indexed | 2024-12-22T02:06:39Z |
| format | Article |
| id | doaj.art-686822ed811f4465b9c7525124cd3451 |
| institution | Directory Open Access Journal |
| issn | 1201-9712 |
| language | English |
| last_indexed | 2024-12-22T02:06:39Z |
| publishDate | 2020-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj.art-686822ed811f4465b9c7525124cd34512022-12-21T18:42:30ZengElsevierInternational Journal of Infectious Diseases1201-97122020-01-0190226233Epidemiological scenario of Q fever hospitalized patients in the Spanish Health System: What’s newBeatriz Rodríguez-Alonso0Hugo Almeida1Montserrat Alonso-Sardón2Amparo López-Bernus3Javier Pardo-Lledias4Virginia Velasco-Tirado5Cristina Carranza-Rodríguez6José Luis Pérez-Arellano7Moncef Belhassen-García8Servicio de Medicina Interna, Complejo Asistencial Universitario de Salamanca, Centro de Investigación de Enfermedades Tropicales de la Universidad de Salamanca (CIETUS), Instituto de Investigación Biomédica de Salamanca (IBSAL), (CAUSA) (CIETUS) (IBSAL), Salamanca, SpainServiço de Medicina Interna, Hospital Sousa Martins, ULS Guarda, Conselho Nacional do Médico Interno, Ordem dos Médicos, SpainÁrea de Medicina Preventiva y Salud Pública, CIETUS, IBSAL, Universidad de Salamanca, Salamanca, SpainServicio de Medicina Interna, CAUSA, CIETUS, IBSAL, Salamanca, SpainServicio de Medicina Interna, Hospital Marques de Valdecilla, CIETUS, Avenida Valdecilla S/N, Santander, SpainServicio de Dermatología, CAUSA, CIETUS, IBSAL, Salamanca, SpainUnidad de Enfermedades Infecciosas y Medicina Tropical, Complejo Hospitalario Universitario Insular-Materno Infantil de Gran Canaria, Las Palmas de Gran Canaria, SpainUnidad de Enfermedades Infecciosas y Medicina Tropical, Complejo Hospitalario Universitario Insular-Materno Infantil de Gran Canaria, Las Palmas de Gran Canaria, SpainServicio de Medicina Interna, Sección de Enfermedades Infecciosas, CAUSA, CIETUS, IBSAL, Universidad de Salamanca, Paseo San Vicente 58-182, 37007, Salamanca, Spain; Corresponding author.Objectives: The objective of this study was to assess the epidemiology and burden of Q fever (QF) in Spain. Methods: We designed a retrospective descriptive study using the minimum basic data set in patients admitted to hospitals of the National Health System between 1998 and 2015 with a diagnosis of Q fever (ICD-9: 083.0.). Results: We found 4214 hospitalized patients with a mean age (±SD) of 50.9 ± 19.3 years. The male/female ratio was 3:1. The incidence rate was between 0.41 and 0.65 cases per 100,000 person-years over the 18-year period. The highest incidence of cases was from March to August (p = 0.024). 21.1% patients had pneumonia, 17.5% had liver disease, and only 3.2% had endocarditis. The average hospital stay was 13.8 days (±12.8). A total of 117 (2.8%) patients died. The total mean cost of QF is approximately €154,232,779 (€36,600 ± 139,422 per patient). Conclusions: QF is an important zoonosis in Spain with a stable incidence rate and high cost for hospitalization. Older patients have a more severe clinical picture and higher mortality, which can be decreased with early clinical suspicion. Keywords: Q fever, Coxiella burnetii, Zoonosis, Pneumonia, Hepatitis, Epidemiologyhttp://www.sciencedirect.com/science/article/pii/S1201971219304370 |
| spellingShingle | Beatriz Rodríguez-Alonso Hugo Almeida Montserrat Alonso-Sardón Amparo López-Bernus Javier Pardo-Lledias Virginia Velasco-Tirado Cristina Carranza-Rodríguez José Luis Pérez-Arellano Moncef Belhassen-García Epidemiological scenario of Q fever hospitalized patients in the Spanish Health System: What’s new International Journal of Infectious Diseases |
| title | Epidemiological scenario of Q fever hospitalized patients in the Spanish Health System: What’s new |
| title_full | Epidemiological scenario of Q fever hospitalized patients in the Spanish Health System: What’s new |
| title_fullStr | Epidemiological scenario of Q fever hospitalized patients in the Spanish Health System: What’s new |
| title_full_unstemmed | Epidemiological scenario of Q fever hospitalized patients in the Spanish Health System: What’s new |
| title_short | Epidemiological scenario of Q fever hospitalized patients in the Spanish Health System: What’s new |
| title_sort | epidemiological scenario of q fever hospitalized patients in the spanish health system what s new |
| url | http://www.sciencedirect.com/science/article/pii/S1201971219304370 |
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