Rhanterium epapposum Oliv. essential oil: Chemical composition and antimicrobial, insect-repellent and anticholinesterase activities
The essential oil (EO) of the aerial parts of Rhanterium epapposum Oliv. (Asteraceae), was obtained by hydrodistillation. The oil was subsequently analyzed by both GC-FID and GC-MS, simultaneously. Forty-five components representing 99.2% of the oil composition were identified. The most abundant com...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2017-07-01
|
| Series: | Saudi Pharmaceutical Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1319016416301141 |
| _version_ | 1818673364812693504 |
|---|---|
| author | Betul Demirci Hasan Soliman Yusufoglu Nurhayat Tabanca Halide Edip Temel Ulrich R. Bernier Natasha M. Agramonte Saleh Ibrahim Alqasoumi Adnan Jathlan Al-Rehaily Kemal Husnu Can Başer Fatih Demirci |
| author_facet | Betul Demirci Hasan Soliman Yusufoglu Nurhayat Tabanca Halide Edip Temel Ulrich R. Bernier Natasha M. Agramonte Saleh Ibrahim Alqasoumi Adnan Jathlan Al-Rehaily Kemal Husnu Can Başer Fatih Demirci |
| author_sort | Betul Demirci |
| collection | DOAJ |
| description | The essential oil (EO) of the aerial parts of Rhanterium epapposum Oliv. (Asteraceae), was obtained by hydrodistillation. The oil was subsequently analyzed by both GC-FID and GC-MS, simultaneously. Forty-five components representing 99.2% of the oil composition were identified. The most abundant compounds were camphene (38.5%), myrcene (17.5%), limonene (10.1%) and α-pinene (8.7%). Referring to the ethnobotanical utilization, an insecticidal assay was performed, where the oil repelled the yellow fever mosquito Aedes aegypti L. at a minimum effective dose (MED of 0.035 ± 0.010 mg/cm2) compared to the positive control DEET (MED of 0.015 ± 0.004 mg/cm2). Additionally, the in vitro antimicrobial activity against a panel of pathogens was determined using a microdilution method. The acetyl- and butyrylcholine esterase inhibitory activities were measured using the colorimetric Ellman method. The bioassay results showed that the oil was rather moderate in antimicrobial and cholinesterase inhibitions when compared to the standard compounds. |
| first_indexed | 2024-12-17T07:54:37Z |
| format | Article |
| id | doaj.art-686a2e94985340a589659d5c12d61044 |
| institution | Directory Open Access Journal |
| issn | 1319-0164 |
| language | English |
| last_indexed | 2024-12-17T07:54:37Z |
| publishDate | 2017-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Saudi Pharmaceutical Journal |
| spelling | doaj.art-686a2e94985340a589659d5c12d610442022-12-21T21:57:46ZengElsevierSaudi Pharmaceutical Journal1319-01642017-07-0125570370810.1016/j.jsps.2016.10.009Rhanterium epapposum Oliv. essential oil: Chemical composition and antimicrobial, insect-repellent and anticholinesterase activitiesBetul Demirci0Hasan Soliman Yusufoglu1Nurhayat Tabanca2Halide Edip Temel3Ulrich R. Bernier4Natasha M. Agramonte5Saleh Ibrahim Alqasoumi6Adnan Jathlan Al-Rehaily7Kemal Husnu Can Başer8Fatih Demirci9Anadolu University, Faculty of Pharmacy, Department of Pharmacognosy, 26470 Eskisehir, TurkeyDepartment of Pharmacognosy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi ArabiaDepartment of Entomology and Nematology, Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USAAnadolu University, Faculty of Pharmacy, Department of Biochemistry, 26470 Eskisehir, TurkeyUSDA-ARS, Center for Medical, Agricultural, and Veterinary Entomology, Gainesville, FL 32608, USADepartment of Entomology and Nematology, Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USADepartment of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi ArabiaDepartment of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi ArabiaAnadolu University, Faculty of Pharmacy, Department of Pharmacognosy, 26470 Eskisehir, TurkeyAnadolu University, Faculty of Pharmacy, Department of Pharmacognosy, 26470 Eskisehir, TurkeyThe essential oil (EO) of the aerial parts of Rhanterium epapposum Oliv. (Asteraceae), was obtained by hydrodistillation. The oil was subsequently analyzed by both GC-FID and GC-MS, simultaneously. Forty-five components representing 99.2% of the oil composition were identified. The most abundant compounds were camphene (38.5%), myrcene (17.5%), limonene (10.1%) and α-pinene (8.7%). Referring to the ethnobotanical utilization, an insecticidal assay was performed, where the oil repelled the yellow fever mosquito Aedes aegypti L. at a minimum effective dose (MED of 0.035 ± 0.010 mg/cm2) compared to the positive control DEET (MED of 0.015 ± 0.004 mg/cm2). Additionally, the in vitro antimicrobial activity against a panel of pathogens was determined using a microdilution method. The acetyl- and butyrylcholine esterase inhibitory activities were measured using the colorimetric Ellman method. The bioassay results showed that the oil was rather moderate in antimicrobial and cholinesterase inhibitions when compared to the standard compounds.http://www.sciencedirect.com/science/article/pii/S1319016416301141Rhanterium epapposumEssential oilBotanical repellentsAntimicrobial activityAChE and BuChE inhibition |
| spellingShingle | Betul Demirci Hasan Soliman Yusufoglu Nurhayat Tabanca Halide Edip Temel Ulrich R. Bernier Natasha M. Agramonte Saleh Ibrahim Alqasoumi Adnan Jathlan Al-Rehaily Kemal Husnu Can Başer Fatih Demirci Rhanterium epapposum Oliv. essential oil: Chemical composition and antimicrobial, insect-repellent and anticholinesterase activities Saudi Pharmaceutical Journal Rhanterium epapposum Essential oil Botanical repellents Antimicrobial activity AChE and BuChE inhibition |
| title | Rhanterium epapposum Oliv. essential oil: Chemical composition and antimicrobial, insect-repellent and anticholinesterase activities |
| title_full | Rhanterium epapposum Oliv. essential oil: Chemical composition and antimicrobial, insect-repellent and anticholinesterase activities |
| title_fullStr | Rhanterium epapposum Oliv. essential oil: Chemical composition and antimicrobial, insect-repellent and anticholinesterase activities |
| title_full_unstemmed | Rhanterium epapposum Oliv. essential oil: Chemical composition and antimicrobial, insect-repellent and anticholinesterase activities |
| title_short | Rhanterium epapposum Oliv. essential oil: Chemical composition and antimicrobial, insect-repellent and anticholinesterase activities |
| title_sort | rhanterium epapposum oliv essential oil chemical composition and antimicrobial insect repellent and anticholinesterase activities |
| topic | Rhanterium epapposum Essential oil Botanical repellents Antimicrobial activity AChE and BuChE inhibition |
| url | http://www.sciencedirect.com/science/article/pii/S1319016416301141 |
| work_keys_str_mv | AT betuldemirci rhanteriumepapposumolivessentialoilchemicalcompositionandantimicrobialinsectrepellentandanticholinesteraseactivities AT hasansolimanyusufoglu rhanteriumepapposumolivessentialoilchemicalcompositionandantimicrobialinsectrepellentandanticholinesteraseactivities AT nurhayattabanca rhanteriumepapposumolivessentialoilchemicalcompositionandantimicrobialinsectrepellentandanticholinesteraseactivities AT halideediptemel rhanteriumepapposumolivessentialoilchemicalcompositionandantimicrobialinsectrepellentandanticholinesteraseactivities AT ulrichrbernier rhanteriumepapposumolivessentialoilchemicalcompositionandantimicrobialinsectrepellentandanticholinesteraseactivities AT natashamagramonte rhanteriumepapposumolivessentialoilchemicalcompositionandantimicrobialinsectrepellentandanticholinesteraseactivities AT salehibrahimalqasoumi rhanteriumepapposumolivessentialoilchemicalcompositionandantimicrobialinsectrepellentandanticholinesteraseactivities AT adnanjathlanalrehaily rhanteriumepapposumolivessentialoilchemicalcompositionandantimicrobialinsectrepellentandanticholinesteraseactivities AT kemalhusnucanbaser rhanteriumepapposumolivessentialoilchemicalcompositionandantimicrobialinsectrepellentandanticholinesteraseactivities AT fatihdemirci rhanteriumepapposumolivessentialoilchemicalcompositionandantimicrobialinsectrepellentandanticholinesteraseactivities |