Infection with hypervirulent Mycobacterium tuberculosis triggers emergency myelopoiesis but not trained immunity

Infection with hypervirulent Mycobacterium tuberculosis triggers emergency myelopoiesis but not trained immunity

IntroductionDuring infection, bone marrow (BM) hematopoiesis is reprogrammed toward myeloid cell production, a mechanism named emergency myelopoiesis. In addition to replenishing myeloid cells, emergency myelopoiesis has been linked to trained immunity, a process that allows enhanced innate immune r...

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Bibliographic Details
Main Authors: Ana Raquel Maceiras, Diogo Silvério, Rute Gonçalves, Marcos S. Cardoso, Margarida Saraiva
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
tuberculosis
myelopoiesis
trained immunity
interferon-gamma
bone marrow
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1211404/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1211404/full

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