The construction of a novel prognostic prediction model for glioma based on GWAS-identified prognostic-related risk loci
Glioma is a highly malignant brain tumor with a grim prognosis. Genetic factors play a role in glioma development. While some susceptibility loci associated with glioma have been identified, the risk loci associated with prognosis have received less attention. This study aims to identify risk loci a...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2024-03-01
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| Series: | Open Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/med-2024-0895 |
| _version_ | 1797258378330767360 |
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| author | Wei Jie Li Yujie Zhou Wenqian Ma Xiaoya Hao Jie Wen Ting Li Bin Jin Tianbo Hu Mingjun |
| author_facet | Wei Jie Li Yujie Zhou Wenqian Ma Xiaoya Hao Jie Wen Ting Li Bin Jin Tianbo Hu Mingjun |
| author_sort | Wei Jie |
| collection | DOAJ |
| description | Glioma is a highly malignant brain tumor with a grim prognosis. Genetic factors play a role in glioma development. While some susceptibility loci associated with glioma have been identified, the risk loci associated with prognosis have received less attention. This study aims to identify risk loci associated with glioma prognosis and establish a prognostic prediction model for glioma patients in the Chinese Han population. |
| first_indexed | 2024-04-24T22:52:35Z |
| format | Article |
| id | doaj.art-686c5a656304494bae4d0d57bb02ac96 |
| institution | Directory Open Access Journal |
| issn | 2391-5463 |
| language | English |
| last_indexed | 2024-04-24T22:52:35Z |
| publishDate | 2024-03-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Medicine |
| spelling | doaj.art-686c5a656304494bae4d0d57bb02ac962024-03-18T10:28:00ZengDe GruyterOpen Medicine2391-54632024-03-011912133410.1515/med-2024-0895The construction of a novel prognostic prediction model for glioma based on GWAS-identified prognostic-related risk lociWei Jie0Li Yujie1Zhou Wenqian2Ma Xiaoya3Hao Jie4Wen Ting5Li Bin6Jin Tianbo7Hu Mingjun8Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi’an 710069, Shaanxi, ChinaKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi’an 710069, Shaanxi, ChinaKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi’an 710069, Shaanxi, ChinaKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi’an 710069, Shaanxi, ChinaKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi’an 710069, Shaanxi, ChinaKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi’an 710069, Shaanxi, ChinaKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi’an 710069, Shaanxi, ChinaKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, Northwest University, Xi’an 710069, Shaanxi, ChinaCollege of Life Science, Northwest University, Xi’an 710127, Shaanxi, ChinaGlioma is a highly malignant brain tumor with a grim prognosis. Genetic factors play a role in glioma development. While some susceptibility loci associated with glioma have been identified, the risk loci associated with prognosis have received less attention. This study aims to identify risk loci associated with glioma prognosis and establish a prognostic prediction model for glioma patients in the Chinese Han population.https://doi.org/10.1515/med-2024-0895glioma prognosisgwasrisk lociprognostic prediction modellasso cox regressionnomogram |
| spellingShingle | Wei Jie Li Yujie Zhou Wenqian Ma Xiaoya Hao Jie Wen Ting Li Bin Jin Tianbo Hu Mingjun The construction of a novel prognostic prediction model for glioma based on GWAS-identified prognostic-related risk loci Open Medicine glioma prognosis gwas risk loci prognostic prediction model lasso cox regression nomogram |
| title | The construction of a novel prognostic prediction model for glioma based on GWAS-identified prognostic-related risk loci |
| title_full | The construction of a novel prognostic prediction model for glioma based on GWAS-identified prognostic-related risk loci |
| title_fullStr | The construction of a novel prognostic prediction model for glioma based on GWAS-identified prognostic-related risk loci |
| title_full_unstemmed | The construction of a novel prognostic prediction model for glioma based on GWAS-identified prognostic-related risk loci |
| title_short | The construction of a novel prognostic prediction model for glioma based on GWAS-identified prognostic-related risk loci |
| title_sort | construction of a novel prognostic prediction model for glioma based on gwas identified prognostic related risk loci |
| topic | glioma prognosis gwas risk loci prognostic prediction model lasso cox regression nomogram |
| url | https://doi.org/10.1515/med-2024-0895 |
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