Data on lung and intestinal microbiome after air pollution exposure in ageing rats
Air pollution has been linked to respiratory diseases, and urban air pollution can be attributed to a number of emission sources. The emitted particles and gases are the primary components of air pollution that enter the lungs during respiration. Particulate matter with an aerodynamic diameter of ≤...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-04-01
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| Series: | Data in Brief |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340923001221 |
| _version_ | 1797867595696701440 |
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| author | Vincent Laiman Yu-Chun Lo Hsin-Chang Chen Tzu-Hsuen Yuan Ta-Chih Hsiao Jen-Kun Chen Ching-Wen Chang Ting-Chun Lin Ssu-Ju Li You-Yin Chen Didik Setyo Heriyanto Kian Fan Chung Kai-Jen Chuang Kin-Fai Ho Jer-Hwa Chang Hsiao-Chi Chuang |
| author_facet | Vincent Laiman Yu-Chun Lo Hsin-Chang Chen Tzu-Hsuen Yuan Ta-Chih Hsiao Jen-Kun Chen Ching-Wen Chang Ting-Chun Lin Ssu-Ju Li You-Yin Chen Didik Setyo Heriyanto Kian Fan Chung Kai-Jen Chuang Kin-Fai Ho Jer-Hwa Chang Hsiao-Chi Chuang |
| author_sort | Vincent Laiman |
| collection | DOAJ |
| description | Air pollution has been linked to respiratory diseases, and urban air pollution can be attributed to a number of emission sources. The emitted particles and gases are the primary components of air pollution that enter the lungs during respiration. Particulate matter with an aerodynamic diameter of ≤ 2.5 µm (PM2.5) can deposit deep into the respiratory tract via inhalation and has been proposed as a causative agent for adverse respiratory health. In addition, the lung contains a diverse microbial community (microbiome) that maintains normal homeostasis and is significantly altered in a variety of pulmonary disorders. Air pollution, specifically PM2.5, has previously been shown to significantly alter the composition of the lower airway microbiome, which has been linked to decreased lung function in chronic obstructive pulmonary disease (COPD) patients. Surprisingly, the intestinal microbiome has also been implicated in the modulation of pulmonary inflammatory diseases. Therefore, dysbiosis of the lung and intestinal microbiomes pose significant negative effects on human health.This dataset describes the microbial community profiles of the lungs and intestines of ageing rats exposed to ambient unconcentrated traffic-related air pollution for three months. The whole-body exposure system was equipped with and without high efficiency particulate air (HEPA) filtration (gaseous vs. PM2.5 pollution). The data can provide valuable information on lung and intestinal microbiome changes, including that which was only found after traffic-related air pollution exposure. |
| first_indexed | 2024-04-09T23:43:43Z |
| format | Article |
| id | doaj.art-686d6a1f6bb94223a93897437edb024c |
| institution | Directory Open Access Journal |
| issn | 2352-3409 |
| language | English |
| last_indexed | 2024-04-09T23:43:43Z |
| publishDate | 2023-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Data in Brief |
| spelling | doaj.art-686d6a1f6bb94223a93897437edb024c2023-03-18T04:41:56ZengElsevierData in Brief2352-34092023-04-0147109004Data on lung and intestinal microbiome after air pollution exposure in ageing ratsVincent Laiman0Yu-Chun Lo1Hsin-Chang Chen2Tzu-Hsuen Yuan3Ta-Chih Hsiao4Jen-Kun Chen5Ching-Wen Chang6Ting-Chun Lin7Ssu-Ju Li8You-Yin Chen9Didik Setyo Heriyanto10Kian Fan Chung11Kai-Jen Chuang12Kin-Fai Ho13Jer-Hwa Chang14Hsiao-Chi Chuang15International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Department of Anatomical Pathology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada – Dr. Sardjito Hospital, Yogyakarta, IndonesiaPh.D. Program in Medical Neuroscience, College of Medical Science and Technology, Taipei Medical University, Taipei, TaiwanDepartment of Chemistry, College of Science, Tunghai University, Taichung, Taiwan.Department of Health and Welfare, College of City Management, University of Taipei, Taipei, TaiwanGraduate Institute of Environmental Engineering, National Taiwan University, Taipei, TaiwanInstitute of Biomedical Engineering & Nanomedicine, National Health Research Institutes, Miaoli, TaiwanIndustrial Ph.D. Program of Biomedical Science and Engineering, National Yang Ming Chiao Tung University, Taipei, TaiwanDepartment of Biomedical Engineering, National Yang Ming Chiao Tung University, Taipei, TaiwanDepartment of Biomedical Engineering, National Yang Ming Chiao Tung University, Taipei, TaiwanPh.D. Program in Medical Neuroscience, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan; Industrial Ph.D. Program of Biomedical Science and Engineering, National Yang Ming Chiao Tung University, Taipei, Taiwan; Department of Biomedical Engineering, National Yang Ming Chiao Tung University, Taipei, TaiwanDepartment of Anatomical Pathology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada – Dr. Sardjito Hospital, Yogyakarta, IndonesiaNational Heart and Lung Institute, Imperial College London, London, UKSchool of Public Health, College of Public Health, Taipei Medical University, Taipei, Taiwan; Department of Public Health, School of Medicine, College of Medicine, Taipei Medical University, Taipei, TaiwanSchool of Public Health and Primary Care, the Chinese University of Hong Kong, Hong KongSchool of Respiratory Therapy, College of Medicine, Taipei Medical University, 250 Wuxing Street, Taipei 11031, Taiwan; Division of Pulmonary Medicine, Departments of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan; Corresponding authors.National Heart and Lung Institute, Imperial College London, London, UK; School of Respiratory Therapy, College of Medicine, Taipei Medical University, 250 Wuxing Street, Taipei 11031, Taiwan; Division of Pulmonary Medicine, Department of Internal Medicine, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan; Cell Physiology and Molecular Image Research Center, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan; Corresponding authors.Air pollution has been linked to respiratory diseases, and urban air pollution can be attributed to a number of emission sources. The emitted particles and gases are the primary components of air pollution that enter the lungs during respiration. Particulate matter with an aerodynamic diameter of ≤ 2.5 µm (PM2.5) can deposit deep into the respiratory tract via inhalation and has been proposed as a causative agent for adverse respiratory health. In addition, the lung contains a diverse microbial community (microbiome) that maintains normal homeostasis and is significantly altered in a variety of pulmonary disorders. Air pollution, specifically PM2.5, has previously been shown to significantly alter the composition of the lower airway microbiome, which has been linked to decreased lung function in chronic obstructive pulmonary disease (COPD) patients. Surprisingly, the intestinal microbiome has also been implicated in the modulation of pulmonary inflammatory diseases. Therefore, dysbiosis of the lung and intestinal microbiomes pose significant negative effects on human health.This dataset describes the microbial community profiles of the lungs and intestines of ageing rats exposed to ambient unconcentrated traffic-related air pollution for three months. The whole-body exposure system was equipped with and without high efficiency particulate air (HEPA) filtration (gaseous vs. PM2.5 pollution). The data can provide valuable information on lung and intestinal microbiome changes, including that which was only found after traffic-related air pollution exposure.http://www.sciencedirect.com/science/article/pii/S2352340923001221Air pollutionLung microbiomeIntestinal microbiomePM2.5 |
| spellingShingle | Vincent Laiman Yu-Chun Lo Hsin-Chang Chen Tzu-Hsuen Yuan Ta-Chih Hsiao Jen-Kun Chen Ching-Wen Chang Ting-Chun Lin Ssu-Ju Li You-Yin Chen Didik Setyo Heriyanto Kian Fan Chung Kai-Jen Chuang Kin-Fai Ho Jer-Hwa Chang Hsiao-Chi Chuang Data on lung and intestinal microbiome after air pollution exposure in ageing rats Data in Brief Air pollution Lung microbiome Intestinal microbiome PM2.5 |
| title | Data on lung and intestinal microbiome after air pollution exposure in ageing rats |
| title_full | Data on lung and intestinal microbiome after air pollution exposure in ageing rats |
| title_fullStr | Data on lung and intestinal microbiome after air pollution exposure in ageing rats |
| title_full_unstemmed | Data on lung and intestinal microbiome after air pollution exposure in ageing rats |
| title_short | Data on lung and intestinal microbiome after air pollution exposure in ageing rats |
| title_sort | data on lung and intestinal microbiome after air pollution exposure in ageing rats |
| topic | Air pollution Lung microbiome Intestinal microbiome PM2.5 |
| url | http://www.sciencedirect.com/science/article/pii/S2352340923001221 |
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