Clinical characteristics and viral etiologies of outpatients with acute respiratory infections in Huzhou of China: a retrospective study
Abstract Background Viruses are commonly found in patients with acute respiratory infections (ARIs). However, the viral etiologies and clinical characteristics of outpatients with ARIs are poorly understood in China. Here, we identified the viral etiologies in outpatients with ARIs in Huzhou, China....
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| Format: | Article |
| Language: | English |
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BMC
2019-01-01
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| Series: | BMC Infectious Diseases |
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| Online Access: | http://link.springer.com/article/10.1186/s12879-018-3668-6 |
| _version_ | 1819229822481596416 |
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| author | Xiaohong Wen Qiuling Huang Hong Tao Weihua Zou Min Gao Huihui Guo Xing Yao Dawei Cui Xiang Wang |
| author_facet | Xiaohong Wen Qiuling Huang Hong Tao Weihua Zou Min Gao Huihui Guo Xing Yao Dawei Cui Xiang Wang |
| author_sort | Xiaohong Wen |
| collection | DOAJ |
| description | Abstract Background Viruses are commonly found in patients with acute respiratory infections (ARIs). However, the viral etiologies and clinical characteristics of outpatients with ARIs are poorly understood in China. Here, we identified the viral etiologies in outpatients with ARIs in Huzhou, China. Results Our results indicated that of 426 outpatients, 246 were positive for viruses. Of them, 221 were positive for a single virus, including influenza A, which comprised H3N2 (28.5%) and pandemic H1N1 (2009) (19.0%), enterovirus (10.4%), and influenza B (8.6%). Other single viruses were detected at less than 8.0%. Twenty-five patients were positively coinfected with two viruses. The prevalent viruses in coinfections were rhinovirus and H3N2 virus (28.0%). Viruses were major pathogens in young children (< 5 years) (75.0%). Coinfections were prevalent in older adults (11.9%) and young children (9.5%). Virus-positive outpatients presented higher temperatures and more sore throat, fatigue and shortness of breath than virus-negative outpatients. ARIs and most virus detections peaked during the winter, but enteroviruses emerged between April and September. Conclusion Viruses are major agents of ARIs among outpatients in Huzhou, China. There was a variation in the distribution of viruses across different age groups and seasons. These findings are beneficial for planning prevention and treatment services for outpatients with ARIs. |
| first_indexed | 2024-12-23T11:19:17Z |
| format | Article |
| id | doaj.art-686de06968ab4525a033184cfe2b0d20 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-12-23T11:19:17Z |
| publishDate | 2019-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-686de06968ab4525a033184cfe2b0d202022-12-21T17:49:07ZengBMCBMC Infectious Diseases1471-23342019-01-011911810.1186/s12879-018-3668-6Clinical characteristics and viral etiologies of outpatients with acute respiratory infections in Huzhou of China: a retrospective studyXiaohong Wen0Qiuling Huang1Hong Tao2Weihua Zou3Min Gao4Huihui Guo5Xing Yao6Dawei Cui7Xiang Wang8The First People’s Hospital Affiliated to Huzhou UniversityDepartment of Clinical Laboratory, Huzhou Central HospitalDepartment of Laboratory & Pharmacy, Suzhou Vocational Health CollegeDepartment of Clinical Laboratory, Huzhou Central HospitalDepartment of Clinical Laboratory, Huzhou Central HospitalThe First People’s Hospital Affiliated to Huzhou UniversityDepartment of Clinical Laboratory, Huzhou Central HospitalDepartment of Blood Transfusion, the First Affiliated Hospital, College of Medicine, Zhejiang UniversityThe First People’s Hospital Affiliated to Huzhou UniversityAbstract Background Viruses are commonly found in patients with acute respiratory infections (ARIs). However, the viral etiologies and clinical characteristics of outpatients with ARIs are poorly understood in China. Here, we identified the viral etiologies in outpatients with ARIs in Huzhou, China. Results Our results indicated that of 426 outpatients, 246 were positive for viruses. Of them, 221 were positive for a single virus, including influenza A, which comprised H3N2 (28.5%) and pandemic H1N1 (2009) (19.0%), enterovirus (10.4%), and influenza B (8.6%). Other single viruses were detected at less than 8.0%. Twenty-five patients were positively coinfected with two viruses. The prevalent viruses in coinfections were rhinovirus and H3N2 virus (28.0%). Viruses were major pathogens in young children (< 5 years) (75.0%). Coinfections were prevalent in older adults (11.9%) and young children (9.5%). Virus-positive outpatients presented higher temperatures and more sore throat, fatigue and shortness of breath than virus-negative outpatients. ARIs and most virus detections peaked during the winter, but enteroviruses emerged between April and September. Conclusion Viruses are major agents of ARIs among outpatients in Huzhou, China. There was a variation in the distribution of viruses across different age groups and seasons. These findings are beneficial for planning prevention and treatment services for outpatients with ARIs.http://link.springer.com/article/10.1186/s12879-018-3668-6Acute respiratory infectionsViral etiologiesCoinfectionsClinical characteristics |
| spellingShingle | Xiaohong Wen Qiuling Huang Hong Tao Weihua Zou Min Gao Huihui Guo Xing Yao Dawei Cui Xiang Wang Clinical characteristics and viral etiologies of outpatients with acute respiratory infections in Huzhou of China: a retrospective study BMC Infectious Diseases Acute respiratory infections Viral etiologies Coinfections Clinical characteristics |
| title | Clinical characteristics and viral etiologies of outpatients with acute respiratory infections in Huzhou of China: a retrospective study |
| title_full | Clinical characteristics and viral etiologies of outpatients with acute respiratory infections in Huzhou of China: a retrospective study |
| title_fullStr | Clinical characteristics and viral etiologies of outpatients with acute respiratory infections in Huzhou of China: a retrospective study |
| title_full_unstemmed | Clinical characteristics and viral etiologies of outpatients with acute respiratory infections in Huzhou of China: a retrospective study |
| title_short | Clinical characteristics and viral etiologies of outpatients with acute respiratory infections in Huzhou of China: a retrospective study |
| title_sort | clinical characteristics and viral etiologies of outpatients with acute respiratory infections in huzhou of china a retrospective study |
| topic | Acute respiratory infections Viral etiologies Coinfections Clinical characteristics |
| url | http://link.springer.com/article/10.1186/s12879-018-3668-6 |
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