Induction of Donor-Specific Transplantation Tolerance to Skin and Cardiac Allografts Using Mixed Chimerism in (A + B → A) in Rats
Mixed allogeneic chimerism (A + B → A) was induced in rats by reconstitution of lethally irradiated LEW recipients with a mixture of T-cell depleted (TCD) syngeneic and TCD allogeneic ACI bone marrow. Thirty-seven percent of animals repopulated as stable mixed lymphopoietic chimeras, while the remai...
Main Authors: | Peter M. Markus M.D., Gennaro Selvaggi, Xin Cai, John J. Fung, Thomas E. Starzl |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
1993-07-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.1177/096368979300200418 |
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