Vector Competence for Dengue-2 Viruses Isolated from Patients with Different Disease Severity
Dynamics of dengue serotype 2 virus isolated from patients with different disease severity, namely flu-like classic dengue fever (DF) and dengue shock syndrome (DSS) were studied in its mosquito vector <i>Aedes aegypti</i>. We compared isolate infectivity and vector competence (VC) among...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-10-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/9/10/859 |
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| author | Ronald Enrique Morales-Vargas Dorothée Missé Irwin F. Chavez Pattamaporn Kittayapong |
| author_facet | Ronald Enrique Morales-Vargas Dorothée Missé Irwin F. Chavez Pattamaporn Kittayapong |
| author_sort | Ronald Enrique Morales-Vargas |
| collection | DOAJ |
| description | Dynamics of dengue serotype 2 virus isolated from patients with different disease severity, namely flu-like classic dengue fever (DF) and dengue shock syndrome (DSS) were studied in its mosquito vector <i>Aedes aegypti</i>. We compared isolate infectivity and vector competence (VC) among thirty two <i>A. aegypti</i>-viral isolate pairs. Mosquito populations from high dengue incidence area exhibited overall greater VC than those from low dengue incidence area at 58.1% and 52.5%, respectively. On the other hand, the overall infection rates for the isolates ThNR2/772 (DF, 62.3%) and ThNR2/391 (DSS, 60.9%), were significantly higher than those for isolates ThNR2/406 (DF, 55.2%) and ThNR2/479 (DSS, 54.8%). These results suggest that the efficacy of dengue virus circulation was likely to vary according to the combination between the virus strains and origin of the mosquito strains, and this may have epidemiologic implications toward the incidence of flu-like classic dengue fever (DF) and dengue shock syndrome (DSS). |
| first_indexed | 2024-03-10T15:27:32Z |
| format | Article |
| id | doaj.art-686e72dbfda3483ca1c6586f759c91d6 |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-10T15:27:32Z |
| publishDate | 2020-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-686e72dbfda3483ca1c6586f759c91d62023-11-20T17:53:55ZengMDPI AGPathogens2076-08172020-10-0191085910.3390/pathogens9100859Vector Competence for Dengue-2 Viruses Isolated from Patients with Different Disease SeverityRonald Enrique Morales-Vargas0Dorothée Missé1Irwin F. Chavez2Pattamaporn Kittayapong3Department of Medical Entomology, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, ThailandMIVEGEC, University Montpellier, IRD, CNRS, 34394 Montpellier, FranceDepartment of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, ThailandCenter for Vectors and Vector-Borne Diseases, Faculty of Science, Mahidol University at Salaya, Nakhon Pathom 73170, ThailandDynamics of dengue serotype 2 virus isolated from patients with different disease severity, namely flu-like classic dengue fever (DF) and dengue shock syndrome (DSS) were studied in its mosquito vector <i>Aedes aegypti</i>. We compared isolate infectivity and vector competence (VC) among thirty two <i>A. aegypti</i>-viral isolate pairs. Mosquito populations from high dengue incidence area exhibited overall greater VC than those from low dengue incidence area at 58.1% and 52.5%, respectively. On the other hand, the overall infection rates for the isolates ThNR2/772 (DF, 62.3%) and ThNR2/391 (DSS, 60.9%), were significantly higher than those for isolates ThNR2/406 (DF, 55.2%) and ThNR2/479 (DSS, 54.8%). These results suggest that the efficacy of dengue virus circulation was likely to vary according to the combination between the virus strains and origin of the mosquito strains, and this may have epidemiologic implications toward the incidence of flu-like classic dengue fever (DF) and dengue shock syndrome (DSS).https://www.mdpi.com/2076-0817/9/10/859dengue virusdisease severityvector competence |
| spellingShingle | Ronald Enrique Morales-Vargas Dorothée Missé Irwin F. Chavez Pattamaporn Kittayapong Vector Competence for Dengue-2 Viruses Isolated from Patients with Different Disease Severity Pathogens dengue virus disease severity vector competence |
| title | Vector Competence for Dengue-2 Viruses Isolated from Patients with Different Disease Severity |
| title_full | Vector Competence for Dengue-2 Viruses Isolated from Patients with Different Disease Severity |
| title_fullStr | Vector Competence for Dengue-2 Viruses Isolated from Patients with Different Disease Severity |
| title_full_unstemmed | Vector Competence for Dengue-2 Viruses Isolated from Patients with Different Disease Severity |
| title_short | Vector Competence for Dengue-2 Viruses Isolated from Patients with Different Disease Severity |
| title_sort | vector competence for dengue 2 viruses isolated from patients with different disease severity |
| topic | dengue virus disease severity vector competence |
| url | https://www.mdpi.com/2076-0817/9/10/859 |
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