Part-Aware Mask-Guided Attention for Thorax Disease Classification

Thorax disease classification is a challenging task due to complex pathologies and subtle texture changes, etc. It has been extensively studied for years largely because of its wide application in computer-aided diagnosis. Most existing methods directly learn global feature representations from whol...

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Main Authors: Ruihua Zhang, Fan Yang, Yan Luo, Jianyi Liu, Jinbin Li, Cong Wang
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Entropy
Subjects:
Online Access:https://www.mdpi.com/1099-4300/23/6/653
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author Ruihua Zhang
Fan Yang
Yan Luo
Jianyi Liu
Jinbin Li
Cong Wang
author_facet Ruihua Zhang
Fan Yang
Yan Luo
Jianyi Liu
Jinbin Li
Cong Wang
author_sort Ruihua Zhang
collection DOAJ
description Thorax disease classification is a challenging task due to complex pathologies and subtle texture changes, etc. It has been extensively studied for years largely because of its wide application in computer-aided diagnosis. Most existing methods directly learn global feature representations from whole Chest X-ray (CXR) images, without considering in depth the richer visual cues lying around informative local regions. Thus, these methods often produce sub-optimal thorax disease classification performance because they ignore the very informative pathological changes around organs. In this paper, we propose a novel Part-Aware Mask-Guided Attention Network (PMGAN) that learns complementary global and local feature representations from all-organ region and multiple single-organ regions simultaneously for thorax disease classification. Specifically, multiple innovative soft attention modules are designed to progressively guide feature learning toward the global informative regions of whole CXR image. A mask-guided attention module is designed to further search for informative regions and visual cues within the all-organ or single-organ images, where attention is elegantly regularized by automatically generated organ masks and without introducing computation during the inference stage. In addition, a multi-task learning strategy is designed, which effectively maximizes the learning of complementary local and global representations. The proposed PMGAN has been evaluated on the ChestX-ray14 dataset and the experimental results demonstrate its superior thorax disease classification performance against the state-of-the-art methods.
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spelling doaj.art-686f85b61c0e4a958d1b749d35d82cd32023-11-21T20:59:07ZengMDPI AGEntropy1099-43002021-05-0123665310.3390/e23060653Part-Aware Mask-Guided Attention for Thorax Disease ClassificationRuihua Zhang0Fan Yang1Yan Luo2Jianyi Liu3Jinbin Li4Cong Wang5School of Computer Science (National Pilot Software Engineering School), Beijing University of Posts and Telecommunications, Beijing 100876, ChinaSchool of Electronics Engineering and Computer Science, Peking University, Beijing 100871, ChinaSchool of Computer Science (National Pilot Software Engineering School), Beijing University of Posts and Telecommunications, Beijing 100876, ChinaSchool of Cyberspace Security, Beijing University of Posts and Telecommunications, Beijing 100876, ChinaLocal Servive Center, National Population Health Data Center, Beijing 100005, ChinaSchool of Computer Science (National Pilot Software Engineering School), Beijing University of Posts and Telecommunications, Beijing 100876, ChinaThorax disease classification is a challenging task due to complex pathologies and subtle texture changes, etc. It has been extensively studied for years largely because of its wide application in computer-aided diagnosis. Most existing methods directly learn global feature representations from whole Chest X-ray (CXR) images, without considering in depth the richer visual cues lying around informative local regions. Thus, these methods often produce sub-optimal thorax disease classification performance because they ignore the very informative pathological changes around organs. In this paper, we propose a novel Part-Aware Mask-Guided Attention Network (PMGAN) that learns complementary global and local feature representations from all-organ region and multiple single-organ regions simultaneously for thorax disease classification. Specifically, multiple innovative soft attention modules are designed to progressively guide feature learning toward the global informative regions of whole CXR image. A mask-guided attention module is designed to further search for informative regions and visual cues within the all-organ or single-organ images, where attention is elegantly regularized by automatically generated organ masks and without introducing computation during the inference stage. In addition, a multi-task learning strategy is designed, which effectively maximizes the learning of complementary local and global representations. The proposed PMGAN has been evaluated on the ChestX-ray14 dataset and the experimental results demonstrate its superior thorax disease classification performance against the state-of-the-art methods.https://www.mdpi.com/1099-4300/23/6/653thorax disease classificationsoft attentionmask-guided attentionmulti-task learning
spellingShingle Ruihua Zhang
Fan Yang
Yan Luo
Jianyi Liu
Jinbin Li
Cong Wang
Part-Aware Mask-Guided Attention for Thorax Disease Classification
Entropy
thorax disease classification
soft attention
mask-guided attention
multi-task learning
title Part-Aware Mask-Guided Attention for Thorax Disease Classification
title_full Part-Aware Mask-Guided Attention for Thorax Disease Classification
title_fullStr Part-Aware Mask-Guided Attention for Thorax Disease Classification
title_full_unstemmed Part-Aware Mask-Guided Attention for Thorax Disease Classification
title_short Part-Aware Mask-Guided Attention for Thorax Disease Classification
title_sort part aware mask guided attention for thorax disease classification
topic thorax disease classification
soft attention
mask-guided attention
multi-task learning
url https://www.mdpi.com/1099-4300/23/6/653
work_keys_str_mv AT ruihuazhang partawaremaskguidedattentionforthoraxdiseaseclassification
AT fanyang partawaremaskguidedattentionforthoraxdiseaseclassification
AT yanluo partawaremaskguidedattentionforthoraxdiseaseclassification
AT jianyiliu partawaremaskguidedattentionforthoraxdiseaseclassification
AT jinbinli partawaremaskguidedattentionforthoraxdiseaseclassification
AT congwang partawaremaskguidedattentionforthoraxdiseaseclassification