Glioblastoma familiar
The authors describe a family with three members affected by glioblastoma. The proband patient, a 7 year-old girl, developed a rare complication, a pulmonary metastasis. Chromosomal analysis of her peripheral blood lymphocytes showed a normal karyotype (46, XX), without structural abnormalities. Cyt...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Academia Brasileira de Neurologia (ABNEURO)
1995-06-01
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| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1995000200025&lng=en&tlng=en |
| _version_ | 1811298924847169536 |
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| author | Walter O. Arruda Rogério S. Clemente Ricardo Ramina Ari A. Pedrozo Rui F. Pilotto Walter Pinto Jr. Luiz F. Bleggi-torres |
| author_facet | Walter O. Arruda Rogério S. Clemente Ricardo Ramina Ari A. Pedrozo Rui F. Pilotto Walter Pinto Jr. Luiz F. Bleggi-torres |
| author_sort | Walter O. Arruda |
| collection | DOAJ |
| description | The authors describe a family with three members affected by glioblastoma. The proband patient, a 7 year-old girl, developed a rare complication, a pulmonary metastasis. Chromosomal analysis of her peripheral blood lymphocytes showed a normal karyotype (46, XX), without structural abnormalities. Cytogenetic study of the tumor cells disclosed several abnormalities: 46, XX, 7q - / 46, XX, -2, 4p-, 7p-, +15/ 46, XX. Some aspects about genetics of glial neoplasms are discussed. |
| first_indexed | 2024-04-13T06:27:33Z |
| format | Article |
| id | doaj.art-68712e182097433ab8b9a97fd1da3087 |
| institution | Directory Open Access Journal |
| issn | 1678-4227 |
| language | English |
| last_indexed | 2024-04-13T06:27:33Z |
| publishDate | 1995-06-01 |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-68712e182097433ab8b9a97fd1da30872022-12-22T02:58:21ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-42271995-06-0153231231710.1590/S0004-282X1995000200025S0004-282X1995000200025Glioblastoma familiarWalter O. ArrudaRogério S. ClementeRicardo RaminaAri A. PedrozoRui F. Pilotto0Walter Pinto Jr.1Luiz F. Bleggi-torres2Universidade Federal do ParanáUniversidade Estadual de CampinasHospital das NaçõesThe authors describe a family with three members affected by glioblastoma. The proband patient, a 7 year-old girl, developed a rare complication, a pulmonary metastasis. Chromosomal analysis of her peripheral blood lymphocytes showed a normal karyotype (46, XX), without structural abnormalities. Cytogenetic study of the tumor cells disclosed several abnormalities: 46, XX, 7q - / 46, XX, -2, 4p-, 7p-, +15/ 46, XX. Some aspects about genetics of glial neoplasms are discussed.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1995000200025&lng=en&tlng=englioblastomacromossomoscitogenéticaoncogênese |
| spellingShingle | Walter O. Arruda Rogério S. Clemente Ricardo Ramina Ari A. Pedrozo Rui F. Pilotto Walter Pinto Jr. Luiz F. Bleggi-torres Glioblastoma familiar Arquivos de Neuro-Psiquiatria glioblastoma cromossomos citogenética oncogênese |
| title | Glioblastoma familiar |
| title_full | Glioblastoma familiar |
| title_fullStr | Glioblastoma familiar |
| title_full_unstemmed | Glioblastoma familiar |
| title_short | Glioblastoma familiar |
| title_sort | glioblastoma familiar |
| topic | glioblastoma cromossomos citogenética oncogênese |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1995000200025&lng=en&tlng=en |
| work_keys_str_mv | AT walteroarruda glioblastomafamiliar AT rogeriosclemente glioblastomafamiliar AT ricardoramina glioblastomafamiliar AT ariapedrozo glioblastomafamiliar AT ruifpilotto glioblastomafamiliar AT walterpintojr glioblastomafamiliar AT luizfbleggitorres glioblastomafamiliar |