Oxidative Stress and Deregulated DNA Damage Response Network in Lung Cancer Patients

Oxidative Stress and Deregulated DNA Damage Response Network in Lung Cancer Patients

The deregulated DNA damage response (DDR) network is associated with the onset and progression of cancer. Herein, we searched for DDR defects in peripheral blood mononuclear cells (PBMCs) from lung cancer patients, and we evaluated factors leading to the augmented formation of DNA damage and/or its...

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Bibliographic Details
Main Authors: Dimitra T. Stefanou, Marousa Kouvela, Dimitris Stellas, Konstantinos Voutetakis, Olga Papadodima, Konstantinos Syrigos, Vassilis L. Souliotis
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomedicines
Subjects:
lung cancer
DNA damage response
oxidative stress
endogenous DNA damage
nucleotide excision repair
double-strand breaks repair
Online Access:https://www.mdpi.com/2227-9059/10/6/1248

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