A Propensity Score Analysis of Early and Long-Term Outcomes of Retrograde Arterial Perfusion for Endoscopic and Minimally Invasive Heart Valve Surgery in Both Young and Elderly Patients

(1) Background: Minimal invasive cardiac surgery via right anterolateral thoracotomy for heart valve surgery and other intracardiac procedures proven to have lower postoperative complications. We aim to compare the neurological complications and post-operative outcomes in two cohort groups as well a...

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Main Authors: Hind Elhassan, Abdelrahman Abdelbar, Rebecca Taylor, Grzegorz Laskawski, Palanikumar Saravanan, Andrew Knowles, Joseph Zacharias
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:https://www.mdpi.com/2308-3425/9/2/44
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author Hind Elhassan
Abdelrahman Abdelbar
Rebecca Taylor
Grzegorz Laskawski
Palanikumar Saravanan
Andrew Knowles
Joseph Zacharias
author_facet Hind Elhassan
Abdelrahman Abdelbar
Rebecca Taylor
Grzegorz Laskawski
Palanikumar Saravanan
Andrew Knowles
Joseph Zacharias
author_sort Hind Elhassan
collection DOAJ
description (1) Background: Minimal invasive cardiac surgery via right anterolateral thoracotomy for heart valve surgery and other intracardiac procedures proven to have lower postoperative complications. We aim to compare the neurological complications and post-operative outcomes in two cohort groups as well as survival rates up to 5 years postoperatively; (2) Methodology: Retrospective observational study for patients who had minimally invasive cardiac valve surgery with retrograde femoral arterial perfusion between 2007 and 2021 (<i>n</i> = 596) and the categorized patients into two groups based on their age (≥70 years old and below 70). Propensity match analysis was conducted. The primary endpoint consisted of major postoperative complications and the secondary endpoint was the long-term survival rate. (3) Results: There was no difference between the two groups in terms of postoperative outcomes. Patients ≥ 70 years old had no increased risk for neurological complications (<i>p</i> = 0.75) compared with those below 70 years old. The mortality rate was also not significant between the two groups (<i>p</i> = 0.37) as well as the crude survival rates. (4) Conclusions: The use of retrograde femoral arterial perfusion in elderly patients is not associated with increased risk compared to the younger patients’ group for a spectrum of primary cardiac valve procedures. Hence, minimally invasive approaches could be offered to elderly patients who might benefit from it.
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spelling doaj.art-688213cacab3438ab2193c2abd6322fd2023-11-23T20:28:18ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252022-01-01924410.3390/jcdd9020044A Propensity Score Analysis of Early and Long-Term Outcomes of Retrograde Arterial Perfusion for Endoscopic and Minimally Invasive Heart Valve Surgery in Both Young and Elderly PatientsHind Elhassan0Abdelrahman Abdelbar1Rebecca Taylor2Grzegorz Laskawski3Palanikumar Saravanan4Andrew Knowles5Joseph Zacharias6Department of Cardiothoracic Surgery, Blackpool Teaching Hospitals NHS Foundation Trust, Whinney Heys Rd, Blackpool FY3 8NR, UKDepartment of Cardiothoracic Surgery, Blackpool Teaching Hospitals NHS Foundation Trust, Whinney Heys Rd, Blackpool FY3 8NR, UKDepartment of Cardiothoracic Surgery, Blackpool Teaching Hospitals NHS Foundation Trust, Whinney Heys Rd, Blackpool FY3 8NR, UKDepartment of Cardiothoracic Surgery, Blackpool Teaching Hospitals NHS Foundation Trust, Whinney Heys Rd, Blackpool FY3 8NR, UKDepartment of Cardiothoracic Surgery, Blackpool Teaching Hospitals NHS Foundation Trust, Whinney Heys Rd, Blackpool FY3 8NR, UKDepartment of Cardiothoracic Surgery, Blackpool Teaching Hospitals NHS Foundation Trust, Whinney Heys Rd, Blackpool FY3 8NR, UKDepartment of Cardiothoracic Surgery, Blackpool Teaching Hospitals NHS Foundation Trust, Whinney Heys Rd, Blackpool FY3 8NR, UK(1) Background: Minimal invasive cardiac surgery via right anterolateral thoracotomy for heart valve surgery and other intracardiac procedures proven to have lower postoperative complications. We aim to compare the neurological complications and post-operative outcomes in two cohort groups as well as survival rates up to 5 years postoperatively; (2) Methodology: Retrospective observational study for patients who had minimally invasive cardiac valve surgery with retrograde femoral arterial perfusion between 2007 and 2021 (<i>n</i> = 596) and the categorized patients into two groups based on their age (≥70 years old and below 70). Propensity match analysis was conducted. The primary endpoint consisted of major postoperative complications and the secondary endpoint was the long-term survival rate. (3) Results: There was no difference between the two groups in terms of postoperative outcomes. Patients ≥ 70 years old had no increased risk for neurological complications (<i>p</i> = 0.75) compared with those below 70 years old. The mortality rate was also not significant between the two groups (<i>p</i> = 0.37) as well as the crude survival rates. (4) Conclusions: The use of retrograde femoral arterial perfusion in elderly patients is not associated with increased risk compared to the younger patients’ group for a spectrum of primary cardiac valve procedures. Hence, minimally invasive approaches could be offered to elderly patients who might benefit from it.https://www.mdpi.com/2308-3425/9/2/44minimal invasive cardiac surgeryretrograde arterial perfusionneurological outcomeelderly patientspropensity score analysis
spellingShingle Hind Elhassan
Abdelrahman Abdelbar
Rebecca Taylor
Grzegorz Laskawski
Palanikumar Saravanan
Andrew Knowles
Joseph Zacharias
A Propensity Score Analysis of Early and Long-Term Outcomes of Retrograde Arterial Perfusion for Endoscopic and Minimally Invasive Heart Valve Surgery in Both Young and Elderly Patients
Journal of Cardiovascular Development and Disease
minimal invasive cardiac surgery
retrograde arterial perfusion
neurological outcome
elderly patients
propensity score analysis
title A Propensity Score Analysis of Early and Long-Term Outcomes of Retrograde Arterial Perfusion for Endoscopic and Minimally Invasive Heart Valve Surgery in Both Young and Elderly Patients
title_full A Propensity Score Analysis of Early and Long-Term Outcomes of Retrograde Arterial Perfusion for Endoscopic and Minimally Invasive Heart Valve Surgery in Both Young and Elderly Patients
title_fullStr A Propensity Score Analysis of Early and Long-Term Outcomes of Retrograde Arterial Perfusion for Endoscopic and Minimally Invasive Heart Valve Surgery in Both Young and Elderly Patients
title_full_unstemmed A Propensity Score Analysis of Early and Long-Term Outcomes of Retrograde Arterial Perfusion for Endoscopic and Minimally Invasive Heart Valve Surgery in Both Young and Elderly Patients
title_short A Propensity Score Analysis of Early and Long-Term Outcomes of Retrograde Arterial Perfusion for Endoscopic and Minimally Invasive Heart Valve Surgery in Both Young and Elderly Patients
title_sort propensity score analysis of early and long term outcomes of retrograde arterial perfusion for endoscopic and minimally invasive heart valve surgery in both young and elderly patients
topic minimal invasive cardiac surgery
retrograde arterial perfusion
neurological outcome
elderly patients
propensity score analysis
url https://www.mdpi.com/2308-3425/9/2/44
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