Successful Treatment of Acute Lethal Dose of Acrylamide Poisoning
Background: Acrylamide (C3H5NO) is a vinyl monomer. This water-soluble crystalline solid is a colorless, odorless agent which is used in scientific laboratories and some industries. Acrylamide has cellular oxidative effects. Acute or chronic poisoning with this agent happens as a result of skin, res...
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| Format: | Article |
| Language: | English |
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Arak University of Medical Sciences
2015-03-01
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| Series: | Iranian Journal of Toxicology |
| Subjects: | |
| Online Access: | http://ijt.arakmu.ac.ir/browse.php?a_id=408&sid=1&slc_lang=en |
| _version_ | 1818934224965599232 |
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| author | Ali Banagozar Mohammadi Hamid Noshad Ali Ostadi Ali Reza Ghaffari Maryam Zaare Nahandi Ahad Banagozar Mohammadi |
| author_facet | Ali Banagozar Mohammadi Hamid Noshad Ali Ostadi Ali Reza Ghaffari Maryam Zaare Nahandi Ahad Banagozar Mohammadi |
| author_sort | Ali Banagozar Mohammadi |
| collection | DOAJ |
| description | Background: Acrylamide (C3H5NO) is a vinyl monomer. This water-soluble crystalline solid is a colorless, odorless agent which is used in scientific laboratories and some industries. Acrylamide has cellular oxidative effects. Acute or chronic poisoning with this agent happens as a result of skin, respiratory, or oral contacts. Clinical manifestations depend on the dose, duration, and frequency of contact. Management of these patients consists of conservative and palliative therapies to reduce the oxidative effects.
Case: The case was a 29-year-old girl with a Master of Sciences degree in genetics who worked in a university research center with previous history of depression. She had ingested 100cc of 30% Acrylamide solution for intentional suicide attempt. The patient was successfully managed using N-acetyl cysteine, vitamin C, and melatonin.
Conclusion: Early diagnosis and appropriate treatment with recommended agents together with supportive therapies can save the life of patients exposed to potentially lethal doses of acrylamide, although intentional or accidental. |
| first_indexed | 2024-12-20T05:00:53Z |
| format | Article |
| id | doaj.art-688abd3cb0f54a3085a3f07e86b837fe |
| institution | Directory Open Access Journal |
| issn | 2008-2967 2251-9459 |
| language | English |
| last_indexed | 2024-12-20T05:00:53Z |
| publishDate | 2015-03-01 |
| publisher | Arak University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Toxicology |
| spelling | doaj.art-688abd3cb0f54a3085a3f07e86b837fe2022-12-21T19:52:33ZengArak University of Medical SciencesIranian Journal of Toxicology2008-29672251-94592015-03-0192812841286Successful Treatment of Acute Lethal Dose of Acrylamide PoisoningAli Banagozar Mohammadi0Hamid Noshad1Ali Ostadi2Ali Reza Ghaffari3Maryam Zaare Nahandi4Ahad Banagozar Mohammadi5Department of Toxicology, Tabriz University of Medical Sciences, Tabriz, Iran.MD. Chronic Kidney Diseases Research Center, Sina Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.*Corresponding Author: E-mail: hamidnoshad1@yahoo.comDepartment of Toxicology, Tabriz University of Medical Sciences, Tabriz, Iran.Philosophy and History of Medicine Research Center, Sina Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.MD. Chronic Kidney Diseases Research Center, Sina Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.Philosophy and History of Medicine Research Center, Sina Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.Background: Acrylamide (C3H5NO) is a vinyl monomer. This water-soluble crystalline solid is a colorless, odorless agent which is used in scientific laboratories and some industries. Acrylamide has cellular oxidative effects. Acute or chronic poisoning with this agent happens as a result of skin, respiratory, or oral contacts. Clinical manifestations depend on the dose, duration, and frequency of contact. Management of these patients consists of conservative and palliative therapies to reduce the oxidative effects. Case: The case was a 29-year-old girl with a Master of Sciences degree in genetics who worked in a university research center with previous history of depression. She had ingested 100cc of 30% Acrylamide solution for intentional suicide attempt. The patient was successfully managed using N-acetyl cysteine, vitamin C, and melatonin. Conclusion: Early diagnosis and appropriate treatment with recommended agents together with supportive therapies can save the life of patients exposed to potentially lethal doses of acrylamide, although intentional or accidental.http://ijt.arakmu.ac.ir/browse.php?a_id=408&sid=1&slc_lang=enAcrylamideAcute PoisoningLethal DoseTreatment |
| spellingShingle | Ali Banagozar Mohammadi Hamid Noshad Ali Ostadi Ali Reza Ghaffari Maryam Zaare Nahandi Ahad Banagozar Mohammadi Successful Treatment of Acute Lethal Dose of Acrylamide Poisoning Iranian Journal of Toxicology Acrylamide Acute Poisoning Lethal Dose Treatment |
| title | Successful Treatment of Acute Lethal Dose of Acrylamide Poisoning |
| title_full | Successful Treatment of Acute Lethal Dose of Acrylamide Poisoning |
| title_fullStr | Successful Treatment of Acute Lethal Dose of Acrylamide Poisoning |
| title_full_unstemmed | Successful Treatment of Acute Lethal Dose of Acrylamide Poisoning |
| title_short | Successful Treatment of Acute Lethal Dose of Acrylamide Poisoning |
| title_sort | successful treatment of acute lethal dose of acrylamide poisoning |
| topic | Acrylamide Acute Poisoning Lethal Dose Treatment |
| url | http://ijt.arakmu.ac.ir/browse.php?a_id=408&sid=1&slc_lang=en |
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