Pancreatic cancer in patient with groove pancreatitis: Potential pitfalls in diagnosis
Pancreatic cancer is among the leading causes of cancer death in the United States of America. Early detection and intervention are critical as a large majority of patients have either local or distant metastatic disease at the time of diagnosis. However, groove pancreatitis, a rare form of chronic...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-12-01
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| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043322007919 |
| _version_ | 1811235355846770688 |
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| author | Elias Lugo-Fagundo, BS Edmund M. Weisberg, MS, MBE Elliot K. Fishman, MD |
| author_facet | Elias Lugo-Fagundo, BS Edmund M. Weisberg, MS, MBE Elliot K. Fishman, MD |
| author_sort | Elias Lugo-Fagundo, BS |
| collection | DOAJ |
| description | Pancreatic cancer is among the leading causes of cancer death in the United States of America. Early detection and intervention are critical as a large majority of patients have either local or distant metastatic disease at the time of diagnosis. However, groove pancreatitis, a rare form of chronic pancreatitis, presents as a challenge for adequate and efficient differential diagnosis of pancreatic cancer as a result of similar clinical symptoms and imaging features. Furthermore, intraductal papillary mucinous neoplasms and pancreatic intraepithelial neoplasia are 2 of the precursor lesions that have been identified with pancreatic ductal adenocarcinoma. Intraductal papillary mucinous neoplasms are cystic tumors of the pancreas characterized by excessive mucin production in either the main pancreatic duct or its branches. Conversely, pancreatic intraepithelial neoplasia are microscopic lesions in the smaller pancreatic ducts. In this article, we report the case of a 46-year-old male with a diagnosis of groove pancreatitis, main duct intraductal papillary mucinous neoplasm, and pancreatic intraepithelial neoplasia whose tumor was excised by means of a Whipple procedure. We focus on optimizing diagnosis and treatment through the application of radiological modalities. |
| first_indexed | 2024-04-12T11:49:27Z |
| format | Article |
| id | doaj.art-688b0b64c35e4c169da7d0b334347491 |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-04-12T11:49:27Z |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-688b0b64c35e4c169da7d0b3343474912022-12-22T03:34:13ZengElsevierRadiology Case Reports1930-04332022-12-01171246324635Pancreatic cancer in patient with groove pancreatitis: Potential pitfalls in diagnosisElias Lugo-Fagundo, BS0Edmund M. Weisberg, MS, MBE1Elliot K. Fishman, MD2Corresponding author.; Johns Hopkins Medicine, The Russell H. Morgan Department of Radiology and Radiological Science, 601 North Caroline Street, Baltimore, MD 21287, USAJohns Hopkins Medicine, The Russell H. Morgan Department of Radiology and Radiological Science, 601 North Caroline Street, Baltimore, MD 21287, USAJohns Hopkins Medicine, The Russell H. Morgan Department of Radiology and Radiological Science, 601 North Caroline Street, Baltimore, MD 21287, USAPancreatic cancer is among the leading causes of cancer death in the United States of America. Early detection and intervention are critical as a large majority of patients have either local or distant metastatic disease at the time of diagnosis. However, groove pancreatitis, a rare form of chronic pancreatitis, presents as a challenge for adequate and efficient differential diagnosis of pancreatic cancer as a result of similar clinical symptoms and imaging features. Furthermore, intraductal papillary mucinous neoplasms and pancreatic intraepithelial neoplasia are 2 of the precursor lesions that have been identified with pancreatic ductal adenocarcinoma. Intraductal papillary mucinous neoplasms are cystic tumors of the pancreas characterized by excessive mucin production in either the main pancreatic duct or its branches. Conversely, pancreatic intraepithelial neoplasia are microscopic lesions in the smaller pancreatic ducts. In this article, we report the case of a 46-year-old male with a diagnosis of groove pancreatitis, main duct intraductal papillary mucinous neoplasm, and pancreatic intraepithelial neoplasia whose tumor was excised by means of a Whipple procedure. We focus on optimizing diagnosis and treatment through the application of radiological modalities.http://www.sciencedirect.com/science/article/pii/S1930043322007919Pancreatic ductal adenocarcinomaIntraductal papillary mucinous neoplasmsPancreatic intraepithelial neoplasiaPancreasGroove pancreatitisWhipple surgery |
| spellingShingle | Elias Lugo-Fagundo, BS Edmund M. Weisberg, MS, MBE Elliot K. Fishman, MD Pancreatic cancer in patient with groove pancreatitis: Potential pitfalls in diagnosis Radiology Case Reports Pancreatic ductal adenocarcinoma Intraductal papillary mucinous neoplasms Pancreatic intraepithelial neoplasia Pancreas Groove pancreatitis Whipple surgery |
| title | Pancreatic cancer in patient with groove pancreatitis: Potential pitfalls in diagnosis |
| title_full | Pancreatic cancer in patient with groove pancreatitis: Potential pitfalls in diagnosis |
| title_fullStr | Pancreatic cancer in patient with groove pancreatitis: Potential pitfalls in diagnosis |
| title_full_unstemmed | Pancreatic cancer in patient with groove pancreatitis: Potential pitfalls in diagnosis |
| title_short | Pancreatic cancer in patient with groove pancreatitis: Potential pitfalls in diagnosis |
| title_sort | pancreatic cancer in patient with groove pancreatitis potential pitfalls in diagnosis |
| topic | Pancreatic ductal adenocarcinoma Intraductal papillary mucinous neoplasms Pancreatic intraepithelial neoplasia Pancreas Groove pancreatitis Whipple surgery |
| url | http://www.sciencedirect.com/science/article/pii/S1930043322007919 |
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