Mapping the emergence of visual consciousness in the human brain via brain-wide intracranial electrophysiology
Consciousness lies at the heart of our existence and experience. To probe how perceptual consciousness emerges in the brain, we recorded brain-wide intracranial electroencephalography signals from human patients while their perceptual consciousness was effectively manipulated using the continuous fl...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-05-01
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| Series: | The Innovation |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S266667582200039X |
| _version_ | 1828490126924185600 |
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| author | Liang Shan Hui Huang Zhiting Zhang Yuyin Wang Fei Gu Mingwei Lu Wen Zhou Yi Jiang Ji Dai |
| author_facet | Liang Shan Hui Huang Zhiting Zhang Yuyin Wang Fei Gu Mingwei Lu Wen Zhou Yi Jiang Ji Dai |
| author_sort | Liang Shan |
| collection | DOAJ |
| description | Consciousness lies at the heart of our existence and experience. To probe how perceptual consciousness emerges in the brain, we recorded brain-wide intracranial electroencephalography signals from human patients while their perceptual consciousness was effectively manipulated using the continuous flash suppression paradigm. We observed substantial differences in brain activities when visual information gradually enters consciousness. Specifically, the functional connectivity first increases and then decreases, oscillations in the low-frequency band reduce in power, and those in the high-frequency band remain unchanged. We employed random forest-based classification to characterize the transitions from no perception to subconsciousness and then to consciousness, which showed an increase in signal variance at the second transition rather than the first. Further, the frontal-parietal junction dominates the first transition, whereas the temporal-frontal lobes dominate the second transition. Finally, we identified the most relevant neuronal features associated with consciousness. Altogether, these findings shed fresh light on the emergence of visual consciousness. |
| first_indexed | 2024-12-11T10:38:07Z |
| format | Article |
| id | doaj.art-688c096f7e7745608d513626ce297def |
| institution | Directory Open Access Journal |
| issn | 2666-6758 |
| language | English |
| last_indexed | 2024-12-11T10:38:07Z |
| publishDate | 2022-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | The Innovation |
| spelling | doaj.art-688c096f7e7745608d513626ce297def2022-12-22T01:10:40ZengElsevierThe Innovation2666-67582022-05-0133100243Mapping the emergence of visual consciousness in the human brain via brain-wide intracranial electrophysiologyLiang Shan0Hui Huang1Zhiting Zhang2Yuyin Wang3Fei Gu4Mingwei Lu5Wen Zhou6Yi Jiang7Ji Dai8Guangdong Provincial Key Laboratory of Brain Connectome and Behavior, CAS Key Laboratory of Brain Connectome and Manipulation, The Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen 518055, China; Corresponding authorDepartment of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang 330006, ChinaGuangdong Provincial Key Laboratory of Brain Connectome and Behavior, CAS Key Laboratory of Brain Connectome and Manipulation, The Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen 518055, ChinaGuangdong Provincial Key Laboratory of Brain Connectome and Behavior, CAS Key Laboratory of Brain Connectome and Manipulation, The Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China; University of Chinese Academy of Sciences, Beijing 100049, ChinaUniversity of Chinese Academy of Sciences, Beijing 100049, China; State Key Laboratory of Brain and Cognitive Science, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, ChinaDepartment of Neurosurgery, The Second Affiliated Hospital of Nanchang University, Nanchang 330006, ChinaUniversity of Chinese Academy of Sciences, Beijing 100049, China; State Key Laboratory of Brain and Cognitive Science, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, ChinaUniversity of Chinese Academy of Sciences, Beijing 100049, China; State Key Laboratory of Brain and Cognitive Science, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China; Corresponding authorGuangdong Provincial Key Laboratory of Brain Connectome and Behavior, CAS Key Laboratory of Brain Connectome and Manipulation, The Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen 518055, China; University of Chinese Academy of Sciences, Beijing 100049, China; Corresponding authorConsciousness lies at the heart of our existence and experience. To probe how perceptual consciousness emerges in the brain, we recorded brain-wide intracranial electroencephalography signals from human patients while their perceptual consciousness was effectively manipulated using the continuous flash suppression paradigm. We observed substantial differences in brain activities when visual information gradually enters consciousness. Specifically, the functional connectivity first increases and then decreases, oscillations in the low-frequency band reduce in power, and those in the high-frequency band remain unchanged. We employed random forest-based classification to characterize the transitions from no perception to subconsciousness and then to consciousness, which showed an increase in signal variance at the second transition rather than the first. Further, the frontal-parietal junction dominates the first transition, whereas the temporal-frontal lobes dominate the second transition. Finally, we identified the most relevant neuronal features associated with consciousness. Altogether, these findings shed fresh light on the emergence of visual consciousness.http://www.sciencedirect.com/science/article/pii/S266667582200039Xvisual consciousnesssubconsciousintracranial electroencephalographyiEEGmachine learningrandom forest |
| spellingShingle | Liang Shan Hui Huang Zhiting Zhang Yuyin Wang Fei Gu Mingwei Lu Wen Zhou Yi Jiang Ji Dai Mapping the emergence of visual consciousness in the human brain via brain-wide intracranial electrophysiology The Innovation visual consciousness subconscious intracranial electroencephalography iEEG machine learning random forest |
| title | Mapping the emergence of visual consciousness in the human brain via brain-wide intracranial electrophysiology |
| title_full | Mapping the emergence of visual consciousness in the human brain via brain-wide intracranial electrophysiology |
| title_fullStr | Mapping the emergence of visual consciousness in the human brain via brain-wide intracranial electrophysiology |
| title_full_unstemmed | Mapping the emergence of visual consciousness in the human brain via brain-wide intracranial electrophysiology |
| title_short | Mapping the emergence of visual consciousness in the human brain via brain-wide intracranial electrophysiology |
| title_sort | mapping the emergence of visual consciousness in the human brain via brain wide intracranial electrophysiology |
| topic | visual consciousness subconscious intracranial electroencephalography iEEG machine learning random forest |
| url | http://www.sciencedirect.com/science/article/pii/S266667582200039X |
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