Outbreak of SARS-CoV-2 B.1.1.7 Lineage after Vaccination in Long-Term Care Facility, Germany, February–March 2021

One week after second vaccinations were administered, an outbreak of B.1.1.7 lineage severe acute respiratory syndrome coronavirus 2 infections occurred in a long-term care facility in Berlin, Germany, affecting 16/20 vaccinated and 4/4 unvaccinated residents. Despite considerable viral loads, vacci...

Full description

Bibliographic Details
Main Authors: Pinkus Tober-Lau, Tatjana Schwarz, David Hillus, Jana Spieckermann, Elisa T. Helbig, Lena J. Lippert, Charlotte Thibeault, Willi Koch, Leon Bergfeld, Daniela Niemeyer, Barbara Mühlemann, Claudia Conrad, Stefanie Kasper, Friederike Münn, Frank Kunitz, Terry C. Jones, Norbert Suttorp, Christian Drosten, Leif Erik Sander, Florian Kurth, Victor M. Corman
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2021-08-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/27/8/21-0887_article
_version_ 1818566958814068736
author Pinkus Tober-Lau
Tatjana Schwarz
David Hillus
Jana Spieckermann
Elisa T. Helbig
Lena J. Lippert
Charlotte Thibeault
Willi Koch
Leon Bergfeld
Daniela Niemeyer
Barbara Mühlemann
Claudia Conrad
Stefanie Kasper
Friederike Münn
Frank Kunitz
Terry C. Jones
Norbert Suttorp
Christian Drosten
Leif Erik Sander
Florian Kurth
Victor M. Corman
author_facet Pinkus Tober-Lau
Tatjana Schwarz
David Hillus
Jana Spieckermann
Elisa T. Helbig
Lena J. Lippert
Charlotte Thibeault
Willi Koch
Leon Bergfeld
Daniela Niemeyer
Barbara Mühlemann
Claudia Conrad
Stefanie Kasper
Friederike Münn
Frank Kunitz
Terry C. Jones
Norbert Suttorp
Christian Drosten
Leif Erik Sander
Florian Kurth
Victor M. Corman
author_sort Pinkus Tober-Lau
collection DOAJ
description One week after second vaccinations were administered, an outbreak of B.1.1.7 lineage severe acute respiratory syndrome coronavirus 2 infections occurred in a long-term care facility in Berlin, Germany, affecting 16/20 vaccinated and 4/4 unvaccinated residents. Despite considerable viral loads, vaccinated residents experienced mild symptoms and faster time to negative test results.
first_indexed 2024-12-14T06:17:21Z
format Article
id doaj.art-689178e7809e49a2984a116167606378
institution Directory Open Access Journal
issn 1080-6040
1080-6059
language English
last_indexed 2024-12-14T06:17:21Z
publishDate 2021-08-01
publisher Centers for Disease Control and Prevention
record_format Article
series Emerging Infectious Diseases
spelling doaj.art-689178e7809e49a2984a1161676063782022-12-21T23:13:58ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592021-08-012782169217310.3201/eid2708.210887Outbreak of SARS-CoV-2 B.1.1.7 Lineage after Vaccination in Long-Term Care Facility, Germany, February–March 2021Pinkus Tober-LauTatjana SchwarzDavid HillusJana SpieckermannElisa T. HelbigLena J. LippertCharlotte ThibeaultWilli KochLeon BergfeldDaniela NiemeyerBarbara MühlemannClaudia ConradStefanie KasperFriederike MünnFrank KunitzTerry C. JonesNorbert SuttorpChristian DrostenLeif Erik SanderFlorian KurthVictor M. CormanOne week after second vaccinations were administered, an outbreak of B.1.1.7 lineage severe acute respiratory syndrome coronavirus 2 infections occurred in a long-term care facility in Berlin, Germany, affecting 16/20 vaccinated and 4/4 unvaccinated residents. Despite considerable viral loads, vaccinated residents experienced mild symptoms and faster time to negative test results.https://wwwnc.cdc.gov/eid/article/27/8/21-0887_articlevaccinemRNAoutbreakphylogenyimmunityT cell
spellingShingle Pinkus Tober-Lau
Tatjana Schwarz
David Hillus
Jana Spieckermann
Elisa T. Helbig
Lena J. Lippert
Charlotte Thibeault
Willi Koch
Leon Bergfeld
Daniela Niemeyer
Barbara Mühlemann
Claudia Conrad
Stefanie Kasper
Friederike Münn
Frank Kunitz
Terry C. Jones
Norbert Suttorp
Christian Drosten
Leif Erik Sander
Florian Kurth
Victor M. Corman
Outbreak of SARS-CoV-2 B.1.1.7 Lineage after Vaccination in Long-Term Care Facility, Germany, February–March 2021
Emerging Infectious Diseases
vaccine
mRNA
outbreak
phylogeny
immunity
T cell
title Outbreak of SARS-CoV-2 B.1.1.7 Lineage after Vaccination in Long-Term Care Facility, Germany, February–March 2021
title_full Outbreak of SARS-CoV-2 B.1.1.7 Lineage after Vaccination in Long-Term Care Facility, Germany, February–March 2021
title_fullStr Outbreak of SARS-CoV-2 B.1.1.7 Lineage after Vaccination in Long-Term Care Facility, Germany, February–March 2021
title_full_unstemmed Outbreak of SARS-CoV-2 B.1.1.7 Lineage after Vaccination in Long-Term Care Facility, Germany, February–March 2021
title_short Outbreak of SARS-CoV-2 B.1.1.7 Lineage after Vaccination in Long-Term Care Facility, Germany, February–March 2021
title_sort outbreak of sars cov 2 b 1 1 7 lineage after vaccination in long term care facility germany february march 2021
topic vaccine
mRNA
outbreak
phylogeny
immunity
T cell
url https://wwwnc.cdc.gov/eid/article/27/8/21-0887_article
work_keys_str_mv AT pinkustoberlau outbreakofsarscov2b117lineageaftervaccinationinlongtermcarefacilitygermanyfebruarymarch2021
AT tatjanaschwarz outbreakofsarscov2b117lineageaftervaccinationinlongtermcarefacilitygermanyfebruarymarch2021
AT davidhillus outbreakofsarscov2b117lineageaftervaccinationinlongtermcarefacilitygermanyfebruarymarch2021
AT janaspieckermann outbreakofsarscov2b117lineageaftervaccinationinlongtermcarefacilitygermanyfebruarymarch2021
AT elisathelbig outbreakofsarscov2b117lineageaftervaccinationinlongtermcarefacilitygermanyfebruarymarch2021
AT lenajlippert outbreakofsarscov2b117lineageaftervaccinationinlongtermcarefacilitygermanyfebruarymarch2021
AT charlottethibeault outbreakofsarscov2b117lineageaftervaccinationinlongtermcarefacilitygermanyfebruarymarch2021
AT willikoch outbreakofsarscov2b117lineageaftervaccinationinlongtermcarefacilitygermanyfebruarymarch2021
AT leonbergfeld outbreakofsarscov2b117lineageaftervaccinationinlongtermcarefacilitygermanyfebruarymarch2021
AT danielaniemeyer outbreakofsarscov2b117lineageaftervaccinationinlongtermcarefacilitygermanyfebruarymarch2021
AT barbaramuhlemann outbreakofsarscov2b117lineageaftervaccinationinlongtermcarefacilitygermanyfebruarymarch2021
AT claudiaconrad outbreakofsarscov2b117lineageaftervaccinationinlongtermcarefacilitygermanyfebruarymarch2021
AT stefaniekasper outbreakofsarscov2b117lineageaftervaccinationinlongtermcarefacilitygermanyfebruarymarch2021
AT friederikemunn outbreakofsarscov2b117lineageaftervaccinationinlongtermcarefacilitygermanyfebruarymarch2021
AT frankkunitz outbreakofsarscov2b117lineageaftervaccinationinlongtermcarefacilitygermanyfebruarymarch2021
AT terrycjones outbreakofsarscov2b117lineageaftervaccinationinlongtermcarefacilitygermanyfebruarymarch2021
AT norbertsuttorp outbreakofsarscov2b117lineageaftervaccinationinlongtermcarefacilitygermanyfebruarymarch2021
AT christiandrosten outbreakofsarscov2b117lineageaftervaccinationinlongtermcarefacilitygermanyfebruarymarch2021
AT leiferiksander outbreakofsarscov2b117lineageaftervaccinationinlongtermcarefacilitygermanyfebruarymarch2021
AT floriankurth outbreakofsarscov2b117lineageaftervaccinationinlongtermcarefacilitygermanyfebruarymarch2021
AT victormcorman outbreakofsarscov2b117lineageaftervaccinationinlongtermcarefacilitygermanyfebruarymarch2021