Tritiated bile acids: problems and recommendations
Kinetic studies of cholic and chenodeoxycholic acids were carried out in three patients by simultaneous intravenous administration of appropriate pairs of 3H- and 14C-labeled compounds. The results obtained indicated two sources of error: chemical impurity and loss of tritium by biological exchange....
Κύριοι συγγραφείς: | , , |
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Μορφή: | Άρθρο |
Γλώσσα: | English |
Έκδοση: |
Elsevier
1974-09-01
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Σειρά: | Journal of Lipid Research |
Θέματα: | |
Διαθέσιμο Online: | http://www.sciencedirect.com/science/article/pii/S0022227520367754 |
Περίληψη: | Kinetic studies of cholic and chenodeoxycholic acids were carried out in three patients by simultaneous intravenous administration of appropriate pairs of 3H- and 14C-labeled compounds. The results obtained indicated two sources of error: chemical impurity and loss of tritium by biological exchange. Precautions are listed for use of tritiated bile acids in studies of pool sizes and turnover rates. |
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ISSN: | 0022-2275 |