Coronally advanced flap with and without hyaluronic acid (HYALOSS) for the treatment of gingival recession – a randomized clinical trial
Objectives: To compare and evaluate the surgical outcome of gingival recession treatment using CAF alone or in conjunction with hyaluronic acid (HA) on Miller's Class I and class II gingival recession defects. Materials and methods: After randomisation, the control group (15 patients) received...
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| Format: | Article |
| Language: | English |
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EDP Sciences
2022-01-01
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| Series: | Journal of Oral Medicine and Oral Surgery |
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| Online Access: | https://www.jomos.org/articles/mbcb/full_html/2022/04/mbcb220043/mbcb220043.html |
| _version_ | 1797951231445958656 |
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| author | Saxena Apoorva Bhusari Prashant Singh Abhilasha Nagi Ravleen Chaturvedi Shailendra Singh |
| author_facet | Saxena Apoorva Bhusari Prashant Singh Abhilasha Nagi Ravleen Chaturvedi Shailendra Singh |
| author_sort | Saxena Apoorva |
| collection | DOAJ |
| description | Objectives: To compare and evaluate the surgical outcome of gingival recession treatment using CAF alone or in conjunction with hyaluronic acid (HA) on Miller's Class I and class II gingival recession defects. Materials and methods: After randomisation, the control group (15 patients) received CAF alone and the test group (15 patients) received HA as an adjunct to CAF technique for an isolated gingival recession accompanied by an adequate width of keratinized gingiva on maxillary canines and premolars. All patients were evaluated at 7, 15, 30, 60 and 90 days interval post-operatively. Data obtained was subjected to statistical analysis and p value <0.05 was considered as statistically significant. Results: At 90 days interval statistically highly significant root coverage was obtained with mean gain of 66.1% in control group and 86.6% in test group. Statistically significant reduction in depth of gingival recession and gain in clinical attachment level was found for control and the test groups, and intergroup comparison showed statistically significant differences for root coverage and clinical attachment level between the groups (p = 0.000), however no significant differences were found for width of attached gingiva, keratinized gingiva and gingival thickness between the groups at 90 days (p > 005). Conclusion: HA has proven to be beneficial in the field of regenerative therapy. Our analysis suggested that HA can be used as a promising adjunct with CAF for root coverage, however further studies are required to imply the results on larger population. |
| first_indexed | 2024-04-10T22:27:23Z |
| format | Article |
| id | doaj.art-68970ab8db5a44e5a804006157d9a1a7 |
| institution | Directory Open Access Journal |
| issn | 2608-1326 |
| language | English |
| last_indexed | 2024-04-10T22:27:23Z |
| publishDate | 2022-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | Journal of Oral Medicine and Oral Surgery |
| spelling | doaj.art-68970ab8db5a44e5a804006157d9a1a72023-01-17T09:01:16ZengEDP SciencesJournal of Oral Medicine and Oral Surgery2608-13262022-01-012844810.1051/mbcb/2022034mbcb220043Coronally advanced flap with and without hyaluronic acid (HYALOSS) for the treatment of gingival recession – a randomized clinical trialSaxena Apoorva0https://orcid.org/0000-0003-1082-2035Bhusari Prashant1https://orcid.org/0000-0001-5203-6433Singh Abhilasha2https://orcid.org/0000-0002-8619-4162Nagi Ravleen3https://orcid.org/0000-0002-0369-1383Chaturvedi Shailendra Singh4https://orcid.org/0000-0003-4786-5039Department of Periodontology, Maitri College of Dentistry and Research CentreDepartment of Periodontology, Maitri College of Dentistry and Research CentrePeriodontist and Implantologist , Dr Bhusari's Dental ClinicDepartment of Oral Medicine and Radiology, Saveetha Dental CollegePeriodontist and Implantologist , Dr Bhusari's Dental ClinicObjectives: To compare and evaluate the surgical outcome of gingival recession treatment using CAF alone or in conjunction with hyaluronic acid (HA) on Miller's Class I and class II gingival recession defects. Materials and methods: After randomisation, the control group (15 patients) received CAF alone and the test group (15 patients) received HA as an adjunct to CAF technique for an isolated gingival recession accompanied by an adequate width of keratinized gingiva on maxillary canines and premolars. All patients were evaluated at 7, 15, 30, 60 and 90 days interval post-operatively. Data obtained was subjected to statistical analysis and p value <0.05 was considered as statistically significant. Results: At 90 days interval statistically highly significant root coverage was obtained with mean gain of 66.1% in control group and 86.6% in test group. Statistically significant reduction in depth of gingival recession and gain in clinical attachment level was found for control and the test groups, and intergroup comparison showed statistically significant differences for root coverage and clinical attachment level between the groups (p = 0.000), however no significant differences were found for width of attached gingiva, keratinized gingiva and gingival thickness between the groups at 90 days (p > 005). Conclusion: HA has proven to be beneficial in the field of regenerative therapy. Our analysis suggested that HA can be used as a promising adjunct with CAF for root coverage, however further studies are required to imply the results on larger population.https://www.jomos.org/articles/mbcb/full_html/2022/04/mbcb220043/mbcb220043.htmlcoronally advanced flapgingival recessionhyaluronic acidroot coverageregeneration |
| spellingShingle | Saxena Apoorva Bhusari Prashant Singh Abhilasha Nagi Ravleen Chaturvedi Shailendra Singh Coronally advanced flap with and without hyaluronic acid (HYALOSS) for the treatment of gingival recession – a randomized clinical trial Journal of Oral Medicine and Oral Surgery coronally advanced flap gingival recession hyaluronic acid root coverage regeneration |
| title | Coronally advanced flap with and without hyaluronic acid (HYALOSS) for the treatment of gingival recession – a randomized clinical trial |
| title_full | Coronally advanced flap with and without hyaluronic acid (HYALOSS) for the treatment of gingival recession – a randomized clinical trial |
| title_fullStr | Coronally advanced flap with and without hyaluronic acid (HYALOSS) for the treatment of gingival recession – a randomized clinical trial |
| title_full_unstemmed | Coronally advanced flap with and without hyaluronic acid (HYALOSS) for the treatment of gingival recession – a randomized clinical trial |
| title_short | Coronally advanced flap with and without hyaluronic acid (HYALOSS) for the treatment of gingival recession – a randomized clinical trial |
| title_sort | coronally advanced flap with and without hyaluronic acid hyaloss for the treatment of gingival recession a randomized clinical trial |
| topic | coronally advanced flap gingival recession hyaluronic acid root coverage regeneration |
| url | https://www.jomos.org/articles/mbcb/full_html/2022/04/mbcb220043/mbcb220043.html |
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