Tropism of Extracellular Vesicles and Cell-Derived Nanovesicles to Normal and Cancer Cells: New Perspectives in Tumor-Targeted Nucleic Acid Delivery

Tropism of Extracellular Vesicles and Cell-Derived Nanovesicles to Normal and Cancer Cells: New Perspectives in Tumor-Targeted Nucleic Acid Delivery

The main advantage of extracellular vesicles (EVs) as a drug carrier system is their low immunogenicity and internalization by mammalian cells. EVs are often considered a cell-specific delivery system, but the production of preparative amounts of EVs for therapeutic applications is challenging due t...

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Bibliographic Details
Main Authors: Anastasiya Oshchepkova, Oleg Markov, Evgeniy Evtushenko, Alexander Chernonosov, Elena Kiseleva, Ksenia Morozova, Vera Matveeva, Lyudmila Artemyeva, Valentin Vlassov, Marina Zenkova
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Pharmaceutics
Subjects:
extracellular vesicles
vesicle mimetic
nucleic acid delivery
cytochalasin B
mesenchymal stem cells
dendritic cells
Online Access:https://www.mdpi.com/1999-4923/13/11/1911

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