Synthesis of Phthalimides: A New Entry via TBAI-Catalyzed Intramolecular Cyclization of 2-(Hydroxymethyl)benzamides

Synthesis of Phthalimides: A New Entry via TBAI-Catalyzed Intramolecular Cyclization of 2-(Hydroxymethyl)benzamides

Abstract Herein we report an unprecedented metal-free TBAI/TBHP mediated C–N bond formation via intramolecular cyclization of 2-(hydroxymethyl)benzamides to furnish N-substituted phthalimides in excellent yields.

Bibliographic Details
Main Authors:	Kare Nagaraju, Nomula Rajesh, Palakodety Radha Krishna
Format:	Article
Language:	English
Published:	Georg Thieme Verlag KG 2018-04-01
Series:	SynOpen
Subjects:	phthalimide intramolecular cyclization transition-metal free c–n bond formation oxidation
Online Access:	http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1609517

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