Gabaergic Interneurons in Early Brain Development: Conducting and Orchestrated by Cortical Network Activity

Gabaergic Interneurons in Early Brain Development: Conducting and Orchestrated by Cortical Network Activity

Throughout early phases of brain development, the two main neural signaling mechanisms—excitation and inhibition—are dynamically sculpted in the neocortex to establish primary functions. Despite its relatively late formation and persistent developmental changes, the GABAergic system promotes the ord...

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Bibliographic Details
Main Authors: Davide Warm, Jonas Schroer, Anne Sinning
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
cortex
development
activity patterns
interneuron
GABA shift
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2021.807969/full

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