Genetic Characteristics and Range of Antibacterial Activity of the Bacteriophages, which are a Part of Manufactured Serie of Drugs - Pyobacteriophage Polyvalent Purified
Pyobacteriophage polyvalent cleared (preparation) is active against 85.0 - 99.6% clinical strains of bacteria Proteus spp., Streptococcus spp., Klebsiella pneumoniae, Escherichia coli, Staphylococcus spp., and Pseudomonas aeruginosa. The preparation surpasses the majority of antibiotics in the width...
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| Format: | Article |
| Language: | Russian |
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Numikom LLC
2016-04-01
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| Series: | Эпидемиология и вакцинопрофилактика |
| Subjects: | |
| Online Access: | https://www.epidemvac.ru/jour/article/view/156 |
| _version_ | 1797879672621498368 |
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| author | N. V. Tikunova N. N. Voroshilov O. A. Polygach V. V. Morozova A. Y. Tikunov A. M. Smokers V. V. Vlasov |
| author_facet | N. V. Tikunova N. N. Voroshilov O. A. Polygach V. V. Morozova A. Y. Tikunov A. M. Smokers V. V. Vlasov |
| author_sort | N. V. Tikunova |
| collection | DOAJ |
| description | Pyobacteriophage polyvalent cleared (preparation) is active against 85.0 - 99.6% clinical strains of bacteria Proteus spp., Streptococcus spp., Klebsiella pneumoniae, Escherichia coli, Staphylococcus spp., and Pseudomonas aeruginosa. The preparation surpasses the majority of antibiotics in the width of a range of antibacterial activity and is comparable only with modern antibiotics of the last generations. Unlike the majority of antibiotics, the preparation doesn't cause toxic and allergic reactions, has no contraindications to application, including age, is allowed for use for newborns and children of early age that gives the chance to regard him as highly effective and safe medicine for antibacterial therapy. The results of metagenomic analysis of pyobacteriophage polyvalent cleared indicate that the product contains only lytic bacteriophages and does not contain lysogenic bacteriophages, that guarantees high concentration of lytic bacteriophages in a preparation high degree of his antibacterial and clinical efficiency and genetic safety of its clinical application. |
| first_indexed | 2024-04-10T02:51:03Z |
| format | Article |
| id | doaj.art-68a0ba57ee3d4e9192ad63aff82f40d2 |
| institution | Directory Open Access Journal |
| issn | 2073-3046 2619-0494 |
| language | Russian |
| last_indexed | 2024-04-10T02:51:03Z |
| publishDate | 2016-04-01 |
| publisher | Numikom LLC |
| record_format | Article |
| series | Эпидемиология и вакцинопрофилактика |
| spelling | doaj.art-68a0ba57ee3d4e9192ad63aff82f40d22023-03-13T07:43:13ZrusNumikom LLCЭпидемиология и вакцинопрофилактика2073-30462619-04942016-04-011529310010.31631/2073-3046-2016-15-2-93-100155Genetic Characteristics and Range of Antibacterial Activity of the Bacteriophages, which are a Part of Manufactured Serie of Drugs - Pyobacteriophage Polyvalent PurifiedN. V. Tikunova0N. N. Voroshilov1O. A. Polygach2V. V. Morozova3A. Y. Tikunov4A. M. Smokers5V. V. Vlasov6ФГБУН «Институт химической биологии и фундаментальной медицины» СО РАНФГБУН «Институт химической биологии и фундаментальной медицины» СО РАНФГБУН «Институт химической биологии и фундаментальной медицины» СО РАНФГБУН «Институт химической биологии и фундаментальной медицины» СО РАНФГБУН «Институт химической биологии и фундаментальной медицины» СО РАНФГБУН «Институт химической биологии и фундаментальной медицины» СО РАНФГБУН «Институт химической биологии и фундаментальной медицины» СО РАНPyobacteriophage polyvalent cleared (preparation) is active against 85.0 - 99.6% clinical strains of bacteria Proteus spp., Streptococcus spp., Klebsiella pneumoniae, Escherichia coli, Staphylococcus spp., and Pseudomonas aeruginosa. The preparation surpasses the majority of antibiotics in the width of a range of antibacterial activity and is comparable only with modern antibiotics of the last generations. Unlike the majority of antibiotics, the preparation doesn't cause toxic and allergic reactions, has no contraindications to application, including age, is allowed for use for newborns and children of early age that gives the chance to regard him as highly effective and safe medicine for antibacterial therapy. The results of metagenomic analysis of pyobacteriophage polyvalent cleared indicate that the product contains only lytic bacteriophages and does not contain lysogenic bacteriophages, that guarantees high concentration of lytic bacteriophages in a preparation high degree of his antibacterial and clinical efficiency and genetic safety of its clinical application.https://www.epidemvac.ru/jour/article/view/156бактериибактериофагиантибиотикиантибактериальная активностьтоксичностьпобочные реакцииbacteriabacteriophagesantibioticstoxicityantibacterial activityside effects |
| spellingShingle | N. V. Tikunova N. N. Voroshilov O. A. Polygach V. V. Morozova A. Y. Tikunov A. M. Smokers V. V. Vlasov Genetic Characteristics and Range of Antibacterial Activity of the Bacteriophages, which are a Part of Manufactured Serie of Drugs - Pyobacteriophage Polyvalent Purified Эпидемиология и вакцинопрофилактика бактерии бактериофаги антибиотики антибактериальная активность токсичность побочные реакции bacteria bacteriophages antibiotics toxicity antibacterial activity side effects |
| title | Genetic Characteristics and Range of Antibacterial Activity of the Bacteriophages, which are a Part of Manufactured Serie of Drugs - Pyobacteriophage Polyvalent Purified |
| title_full | Genetic Characteristics and Range of Antibacterial Activity of the Bacteriophages, which are a Part of Manufactured Serie of Drugs - Pyobacteriophage Polyvalent Purified |
| title_fullStr | Genetic Characteristics and Range of Antibacterial Activity of the Bacteriophages, which are a Part of Manufactured Serie of Drugs - Pyobacteriophage Polyvalent Purified |
| title_full_unstemmed | Genetic Characteristics and Range of Antibacterial Activity of the Bacteriophages, which are a Part of Manufactured Serie of Drugs - Pyobacteriophage Polyvalent Purified |
| title_short | Genetic Characteristics and Range of Antibacterial Activity of the Bacteriophages, which are a Part of Manufactured Serie of Drugs - Pyobacteriophage Polyvalent Purified |
| title_sort | genetic characteristics and range of antibacterial activity of the bacteriophages which are a part of manufactured serie of drugs pyobacteriophage polyvalent purified |
| topic | бактерии бактериофаги антибиотики антибактериальная активность токсичность побочные реакции bacteria bacteriophages antibiotics toxicity antibacterial activity side effects |
| url | https://www.epidemvac.ru/jour/article/view/156 |
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