Amelioration of Cognitive Deficit by Embelin in a Scopolamine-Induced Alzheimer’s Disease-Like Condition in a Rat Model

Amelioration of Cognitive Deficit by Embelin in a Scopolamine-Induced Alzheimer’s Disease-Like Condition in a Rat Model

Embelin (2,5-dihydroxy-3-undecyl-1,4-benzoquinone) is one of the active components (2.3%) found in Embelia ribes Burm fruits. As determined via in vitro AChE inhibition assay, embelin can inhibit the acetylcholinesterase enzyme. Therefore, embelin can be utilized as a therapeutic compound, after fur...

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Bibliographic Details
Main Authors: Saatheeyavaane Bhuvanendran, Yatinesh Kumari, Iekhsan Othman, Mohd Farooq Shaikh
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Pharmacology
Subjects:
embelin
Alzheimer’s disease
cognition
neuroprotective
anti-amnesic effect
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00665/full

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