Genetic proxies for antihypertensive drugs and mental disorders: Mendelian randomization study in European and East Asian populations

Genetic proxies for antihypertensive drugs and mental disorders: Mendelian randomization study in European and East Asian populations

Abstract Background Mental disorders are among the top causes of disease burden worldwide. Existing evidence regarding the repurposing of antihypertensives for mental disorders treatment is conflicting and cannot establish causation. Methods We used Mendelian randomization to assess the effects of a...

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Bibliographic Details
Main Authors: Bohan Fan, Jie V. Zhao
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Medicine
Subjects:
Antihypertensive drugs
Mental disorders
Mendelian randomization
Online Access:https://doi.org/10.1186/s12916-023-03218-6

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