Matrix-free human pluripotent stem cell manufacturing by seed train approach and intermediate cryopreservation

Matrix-free human pluripotent stem cell manufacturing by seed train approach and intermediate cryopreservation

Abstract Background Human pluripotent stem cells (hPSCs) have an enormous therapeutic potential, but large quantities of cells will need to be supplied by reliable, economically viable production processes. The suspension culture (three-dimensional; 3D) of hPSCs in stirred tank bioreactors (STBRs) h...

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Bibliographic Details
Main Authors: Kevin Ullmann, Felix Manstein, Wiebke Triebert, Nils Kriedemann, Annika Franke, Jana Teske, Mira Mertens, Victoria Lupanow, Gudrun Göhring, Alexandra Haase, Ulrich Martin, Robert Zweigerdt
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Stem Cell Research & Therapy
Subjects:
hPSC
STBR
Suspension culture
Intermediate cryopreservation
Seed train
Aggregate dissociation
Online Access:https://doi.org/10.1186/s13287-024-03699-z

Internet

https://doi.org/10.1186/s13287-024-03699-z

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