Modulation of Function, Structure and Clustering of K<sup>+</sup> Channels by Lipids: Lessons Learnt from KcsA

Modulation of Function, Structure and Clustering of K<sup>+</sup> Channels by Lipids: Lessons Learnt from KcsA

KcsA, a prokaryote tetrameric potassium channel, was the first ion channel ever to be structurally solved at high resolution. This, along with the ease of its expression and purification, made KcsA an experimental system of choice to study structure–function relationships in ion channels. In fact, m...

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Bibliographic Details
Main Authors: María Lourdes Renart, Ana Marcela Giudici, Clara Díaz-García, María Luisa Molina, Andrés Morales, José M. González-Ros, José Antonio Poveda
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
lipid–protein interactions
C-type inactivation
membrane protein folding
ion channel clustering
ion binding
KcsA modulation
Online Access:https://www.mdpi.com/1422-0067/21/7/2554

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